Unilateral Primary Adrenal Diffuse Large B- Cell Lymphoma with Metastatic Nodule on Spleen – A Rare Case Report.
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2019, Vol 4, Issue 5
Abstract
Primary haematolymphoid tumours involving the adrenal gland are infrequent and are mainly lymphomas. Primary adrenal lymphoma (PAL) is uncommon in clinical settings, and is considered as a rare high grade malignant lymphoma with poor prognosis. Patients with unilateral mass with normal adrenal functioning are extremely rare. Patient may show secondary involvement of lymph nodes, bones, spleen, lungs, gastrointestinal tract, central nervous system and other endocrine organs. We report a case of a 49year post-menopausal female presented with left lumbar quadrant abdominal pain. Local examination showed firm palpable lump on deep palpation. Haematological and biochemical profile was within normal limits. Abdominal ultrasonography and abdominopelvic CT showed an enlarged left adrenal mass, likely of a neoplastic etiology with abdominal pre and para-aortic lymphadenopathy. Histopathological examination and immunohistochemistry confirmed the diagnosis of Diffuse Large B -Cell Lymphoma of the left adrenal gland with secondary involvement of splenic nodules. The present study highlights rare occurrence of primary adrenal lymphoma as the unilateral adrenal mass with secondary involvement of splenic nodules.
Authors and Affiliations
Dr. Mrinalini Dhotre
Keywords
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