Unmasking Immune Reconstitution Inflammatory Syndrome (IRIS) A report of five cases and review of the literature
Journal Title: Sultan Qaboos University Medical Journal - Year 2011, Vol 11, Issue 1
Abstract
Immune reconstitution inflammatory syndromes (IRIS) in patients with acquired immune defciency syndrome (AIDS) are characterised by atypical manifestations of opportunistic pathogens. Tese occur in patients experiencing improvement in CD4 cell counts following receipt of highly active anti-retroviral therapy (HAART). Although well established as a syndrome, IRIS still presents challenges in diagnosis and management. We report fve cases of IRIS with diverse clinical presentations and due to different infectious aetiologies. A review of the published literature on this syndrome is also included.
Authors and Affiliations
Abdullah Balkhair| Department of Medicine, Sultan Qaboos University Hospital, Muscat, Oman, Sudheer Ahamed| Department of Medicine, Sultan Qaboos University Hospital, Muscat, Oman, Dilip Sankhla| Department of Medicine, Sultan Qaboos University Hospital, Muscat, Oman
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