Unruptured Intracranial Aneurysm in ADPKD: An Overview with Illustrative Report of Three Cases
Journal Title: Nepal Journal of Neuroscience - Year 2013, Vol 10, Issue 2
Abstract
Autosomal dominant polycystic kidney disease (ADPKD) is a common single gene hereditary disorder characterized by progressive development of bilateral renal cysts eventually leading to chronic kidney disease and an array of extrarenal abnormalities including intracranial aneurysm (ICAN). While the association of ICAN with ADPKD is undisputed, its management is not standardized. Conflicting data about the benefits of screening to the efficacy of different treatment modalities have not helped establish any opinion. We report three such cases managed surgically at Hiroshima University Hospital and discuss and review the literature regarding ADPKD and ICAN. Decision for surgical management of these cases were multifactorial and not exclusively because of ADPKD. There is a lack of sufficient randomized data on these topics and until such results are available, neurosurgeons are likely to resort to bit-part data and weigh the risk-benefit factor in individual patients and proceed accordingly.
Authors and Affiliations
Rupendra B Adhikari, MD
Keywords
Related Articles
- EP ID EP368877
- DOI -
- Views 127
- Downloads 0
Initial experience with aneurysm coiling in Nepal.
The aim of this study is to show the result of aneurysm coiling despite the diffi culty in initiating neurointervention in Nepal.It is a retrospective study where only aneurysm that has undergone coiling are taken from 2...
Initial Experience of Different Surgical Techniques in Temporal Lobe Epilepsy in Nepal
An initial experience of different surgical techniques in intractable temporal lobe epilepsy (TLE) secondary to mesial temporal sclerosis (MTS) is presented. We resorted to surgery in 4 cases of TLE when all other means...
Outcome Difference in Neurosurgical Patients Based on Timing of Tracheostomy and Ventilator Associated Pneumonia
neurosurgical patients has been shown in various studies to lower the length of ICU stay and the length of hospital stay by decreasing the incidence of ventilator associated pneumonia. In this regard, we wanted to evalua...
Scientific Round-up
No data
An Audit of Head Injury at Bir Hospital
Bir Hospital receives many trauma patients of which high proportion are head injuries. Over the last 30 years there have been improvements in the provision of care and facilities available at Bir Hospital. It is a high t...