Unusual Alveolar Pattern in Node Based Diffuse Large B-cell Lymphoma
Journal Title: Journal of Krishna Institute of Medical Sciences University - Year 2017, Vol 6, Issue 1
Abstract
Diffuse Large B-cell Lymphoma (DLBCL) is the most common subtype of non-Hodgkin’s lymphoma worldwide. We present a case of 45 year old male patient presenting with swelling in right side of the neck since 6 months. A cytological aspirate of the lymph node suggested possibility of malignancy and excision biopsy was advised. Histopathology revealed a well-developed alveolar pattern with nests of dyscohesive large round tumour cells separated by delicate fibrovascular septae. Tumour cells were positive for CD45, CD20 and BCL-6 and negative for CD3, CD 5, CD 10, BCL-2, Desmin, Chromogranin, Synaptophysin and S-100. Based on histopathology and immunohistochemical findings, final diagnosis of DLBCL, NOS was given. The case is presented to highlight an unusual morphological alveolar growth pattern in DLBCL.
Authors and Affiliations
Archana C Buch, Jay Y Sheth, Sunita A Bamanikar, Aditi A Pandey
Keywords
Related Articles
- EP ID EP228232
- DOI -
- Views 88
- Downloads 0
Laparoscopic Assisted Transperitoneal Percutaneous Nephrolithotomy for Stones in Pelvic Kidney
The most common form of renal ectopy is pelvic kidney and treating stone disease and achieving complete stone clearance in such anatomical anomaly is difficult. We report a case of patient with pain in left iliac fos...
Omohyoid Muscle: An Anatomical Study
Background: Variants of the omohyoid muscle are essential, because of their close relationship with the great vessels and brachial plexus. Due to direct attachment of the tendon to the wall of the internal jugular vein,...
Viral Diseases of Public Health Importance in India: Current Priorities with Special Emphasis on Prevention
India faces problems with both communicable and non communicable diseases. The major non communicable diseases are cancer, cardiovascular disease and diabetes mellitus. This article focuses on communicable diseases (infe...
Disposal of Bio-medical Waste in India
Neurodiagnostic Evaluation of a Child with First Complex Febrile Seizure
Background: Febrile seizure is the most common type of childhood seizure and complex febrile seizure has been associated with the risk of epilepsy. The neurodiagnostic evaluation of a child with first CFS is still un...