Unusual presentation of JAK2-negative polycythemia
Journal Title: Indian Journal of Case Reports - Year 2018, Vol 4, Issue 3
Abstract
Polycythemia vera is a relatively rare disease occurring in 0.02–2.8 per million population. Globally, about 95% of PV is due to JAK2V617F mutation in the chromosome 9p. The remaining 5% were found to have a wide range of mutations including JAK2 exon12 mutation and calreticulin (CALR) mutation. In India, the incidence of JAK2-negative polycythemia is relatively high, reaching up to 18%. Polycythemia usually presents as symptoms secondary to hyperviscosity or as symptoms secondary to increased histamine release by the cells. Herein, we describe a 46-year-old Indian male presented with a headache and found to be in hypertensive urgency, which was later found to be secondary to JAK2-negative polycythemia.
Authors and Affiliations
Akesh Thomas, Alex Robert, Don Babu Chemplavil
Keywords
Related Articles
- EP ID EP500522
- DOI -
- Views 88
- Downloads 0
Sjogren’s syndrome presenting with recurrent hypokalemic paralysis
Sjogren’s syndrome is an autoimmune disorder commonly affecting females and presents with the dryness of the mouth and eyes. Here, we present an interesting case of Sjogren’s syndrome, initial presentation with distal re...
Poland syndrome with some rare associations, and brief literature review
Poland syndrome (PS) is a rare congenital condition with predominant unilateral chest wall deformity due to hypoplasia of the pectoralis muscles. However, its clinical features are highly variable as all the features may...
Ureteral obstruction by an aberrant renal artery: A case report
The ureter is a muscular tubular structure that carries urine from the kidney to the urinary bladder. It is usually about 20–25 cm in length and 3–5 mm diameter. The upper half lies in the belly and the lower half in the...
A rare case of indirect inguinal hernia with ovary as content at a hospital of Visakhapatnam
A hernia is the protrusion of the small intestines or omentum or other organs through a defect in the abdominal wall. Inguinal hernia in females is very rare and occurs in <5% of women. Here, we report the case of a 25-y...
Multiple cerebral abscesses in decompensated cirrhosis of liver as a mimicker of hepatic encephalopathy: A case report
Cirrhosis of the liver is a state of immune dysregulation. It can give way to many infections. Brain abscess, though uncommonly reported in cirrhotic patients, deserves special attention as it presents a diagnostic and t...