Update and critical appraisal of topical azithromycin ophthalmic 1%(Azasite) solution in the treatment of ocular infections
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
Azithromycin is an azalide that acts by binding to the 50S ribosomal subunit of susceptible microorganisms and interfering with microbial protein synthesis. Azithromycin is also noted by antiinflammatory and immunomodulatory activity. AzaSite® (Inspire Pharmaceuticals, Inc, Durham, NC) is azithromycin ophthalmic solution, 1% formulated in polycarbophil (the aqueous mucoadhesive polymer contained in DuraSite®) that delivers high and prolonged azithromycin concentrations in a variety of ocular tissues, including the conjunctiva, cornea and particularly the eyelid. AzaSite was approved by the Food and Drug Administration (FDA) in the US in 2007, for the treatment of bacterial conjunctivitis caused by susceptible isolates. This article aims to evaluate the peer-reviewed published scientific literature and to define well established uses of AzaSite eye drops in the field of ocular infections.
Authors and Affiliations
Dr. Rakesh Kumar, Dr. Kanchan Mala
Keywords
Related Articles
- EP ID EP571015
- DOI 10.9790/0853-1801151622.
- Views 56
- Downloads 0
Intestinal Malrotation: Experience with Diagnosis And Management of 76 Patients from A Tertiary Care Centre in India
Introduction: Malrotation is a spectrum of anatomical abnormalities due to incomplete rotation and fixation of intestine during the embryonic development. The clinical presentation varies from off and on symptoms of high...
Maxillary Paramolar: Case Report And Overview
Paramolar is a type of supernumerary teeth that is small and mostly situated buccally or adjacent to maxillary molars. It is a type of developmental disturbance that can occur due to varied etiology. In this case report,...
Review of cases involving forensic odontology and its relevance in world statistics: an original study
Forensic odontology usually involves the cooperation & coordination of law enforcement officials, forensic pathologists, forensic odontologists, forensic anthropologists, serologists, criminalistics, & other specialists....
Sonographic Evaluation of Developmental Hip Dysplasia using Graf’s Method
The aim of the current study was to evaluate the hip joint for infants who were clinically diagnosed to have Developmental hip dysplasia (DDH) focusing mostly on the Graf’s method using ultrasonography, by measuring the...
A Complex Fistula-in-Ano Presenting As A Sinus Right Side of Lower Back
Anal fistula is among the most common illnesses affecting man. The majority of fistulas unrelated to specific causes (eg. Tuberculosis, Crohn’s disease) result from infection (abscess) in anal glands extending from the i...