Update of pathology in medullary thyroid carcinoma

Journal Title: Journal of Surgery : Concepts & Practice - Year 2023, Vol 28, Issue 6

Abstract

Medullary thyroid carcinoma (MTC) is a rare thyroid malignancy, which is more aggressive with high metastasis and recurrence rate. Surgical treatment is the preferred treatment option for MTC. Targeted therapy and immunotherapy have gradually become new treatment strategy for MTC. The pathology of MTC was updated in the 5th edition WHO classification of endocrine and neuroendocrine tumor in 2022. This review summarized the update of MTC pathology focusing on the histologic grading schemes, gene screening and genetic counseling.

Authors and Affiliations

Zhiyan LIU, Yaling YU, Kennichi KAKUDO

Keywords

Related Articles

KRAS genotypes predict metachronous colorectal cancer distant metastases after radical resections

[Objective] To explore the relationship between KRAS genotype and metachronous distant metastases in patients with colorectal cancer after radical resections. [Methods] Patients were analyzed retrospectively with metachr...

Preoperative chemotherapy through intra-arterial combined with intra-venous administration in treatment of advanced gastric cancer

Perioperative chemotherapy has been an important part of the comprehensive treatment of advanced gastric cancer. Different from the conventional systemic chemotherapy, preoperative chemotherapy through intra-arterial com...

Summary and prospect of perioperative comprehensive treatment for gastric cancer in China

Most of the patients with gastric cancer in China have been at the middle and advanced stages during diagnostic and treatment with poor prognosis overall. Perioperative radiotherapy, chemotherapy, immune therapy and othe...

Clinical significance of combination of anti-angiogenesis, immune checkpoint inhibitors and chemotherapy in the neoadjuvant treatment of locally advanced gastric cancer

The combination of anti-angiogenesis, immune checkpoint inhibitors(ICIs) and chemotherapy(target-immune-chemo) has achieved initial results in the comprehensive treatment of gastric cancer. Experimental studies have show...

Download PDF file
  • EP ID EP750921
  • DOI 10.16139/j.1007-9610.2023.06.03
  • Views 17
  • Downloads 1

How To Cite

Zhiyan LIU, Yaling YU, Kennichi KAKUDO (2023). Update of pathology in medullary thyroid carcinoma. Journal of Surgery : Concepts & Practice, 28(6), -. https://europub.co.uk/articles/-A-750921