Update of pathology in medullary thyroid carcinoma
Journal Title: Journal of Surgery : Concepts & Practice - Year 2023, Vol 28, Issue 6
Abstract
Medullary thyroid carcinoma (MTC) is a rare thyroid malignancy, which is more aggressive with high metastasis and recurrence rate. Surgical treatment is the preferred treatment option for MTC. Targeted therapy and immunotherapy have gradually become new treatment strategy for MTC. The pathology of MTC was updated in the 5th edition WHO classification of endocrine and neuroendocrine tumor in 2022. This review summarized the update of MTC pathology focusing on the histologic grading schemes, gene screening and genetic counseling.
Authors and Affiliations
Zhiyan LIU, Yaling YU, Kennichi KAKUDO
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