Updates on the Conflict of Postoperative Radiotherapy Impact on Survival of Young Women with Cancer Breast: A Retrospective Cohort Study
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2017, Vol 6, Issue 7
Abstract
Purpose: The purpose of the present study is to investigate the impact of postoperative radiotherapy on the survival of young women aged 25-29 years diagnosed with different stages of breast cancer. Methods: We conducted a retrospective cohort study that included young women diagnosed with breast cancer from SEER database. The total analytical sample of the present study (n=4153) was divided into two separate groups; intervention group (n=1814) who did receive postoperative radiation therapy (PORT) and control group (n=2339) who did not receive PORT. Chi square test and Kaplan Meier method had been carried out for statistical analysis. Results: Relative survival rate of the intervention group, estimated by Kaplan-Meier method was found to be (62.9%, CI 95%) for breast cancer stage I, (66.1%, CI 95%) and (58.2%, CI 95%) for stages IIA, and IIB respectively. (30.9%, CI 95%) (54%, CI 95%) and (32.1%, CI 95%) for breast cancer stages IIIA, IIIB, and IIIC respectively and (10.3%, CI 95%) for breast cancer stage IV. Conclusion: Postoperative adjuvant radiotherapy shows a signifcant positive impact on overall survival of young women diagnosed with breast cancer stages III, and IV (P<0.05). Moreover, no signifcant impact on survival was noted for breast cancer stages I, and II.
Authors and Affiliations
Hassan Mohamed Eweidah| Faculty of Medicine, Alexandria University, Alexandria, Egypt, Corresponding e-mail: h_Awaeda2121066@alexmed.edu.eg, Anis Sameh Hanna| Faculty of Medicine, Alexandria University, Alexandria, Egypt, Ahmed Mohamed Eweidah| Faculty of Medicine, Alexandria University, Alexandria, Egypt, Hazem Abdullah El-Sheikh| Faculty of Medicine, Alexandria University, Alexandria, Egypt
Keywords
Related Articles
- EP ID EP12402
- DOI -
- Views 299
- Downloads 14
PRO AND ANTI-INFLAMMATORY EFFECTS OF GRADED PHYSICAL EXERCISE
Background: It is generally believed that exercise is good for health. Exercise can be harmful to immune system depending on type and duration. So it was decided to study the plasma levels of cytokines with increasing s...
STROKE IN A CHILD AS A COMPLICATION OF IRON DEFICIENCY ANEMIA: A CASE REPORT
Stroke is characterized by the sudden loss of blood circulation to an area of the brain, resulting in monoparesis, hemi paresis and dysphasia. Nutritional anemia is a common problem all over the world. Especially Iron...
DERMATOGLYPHICS: A PREDICTOR TOOL TO ANALYZE THE OCCURRENCE OF BREAST CANCER
Background: Dermatoglyphics is the branch of science that deals with the study of ridge patterns on finger tips, palm, sole and toes and when once formed, they remain unchanged throughout the except after severe injurie...
Impact of Predisposing Factors on Academic Stress among Pre-Service Teachers
Background: Many studies have been done on stress among educators. Teachers, lecturers, and tutors all over the world has been brought into attention when it comes to stress related issues. Our purpose was to investigat...
A STUDY ON CORRELATION BETWEEN POSTERIOR CAPSULAR OPACIFICATION AND VISUAL FUNCTION BEFORE AND AFTER NEODYMIUM: YAG LASER POSTERIOR CAPSULOTOMY IN RURAL POPULATION OF NORTH MAHARASHTRA
Posterior capsular opacification is the opacity which follows after extra capsular cataract extraction and can be treated by surgery or laser. The laser is the procedure of choice because it is non invasive, outpatient...