Uric acid and lipid ratios in lean normoglycemic patients of chronic kidney disease
Journal Title: Medpulse International Journal of Biochemistry - Year 2017, Vol 4, Issue 2
Abstract
Objectives: To investigate the derangement of lipid ratios in normoglycemic lean chronic kidney disease patients. To find out the correlation of uric acid with the lipid ratios. Materials and Methods: 50 lean (BMI <25) normoglycemic patients with chronic kidney disease having calculated GFR <75 ml/min/1.73 m2 comprised the study group and 50 normal lean (BMI < 25) healthy age and sex matched subjects comprised the control group. Serum uric acid and lipid profile are measured by using commercially available kits on semi automatic analyser. Results: We found that TC/HDL, LDL/HDL and TG/HDL ratio are statistically significantly elevated in study group than in controls. The elevated serum uric acid was significantly positively correlated with TG/HDL ratio. Conclusion: Serum uric acid is significantly associated with TG/HDL ratio in lean and normoglycemic patients of chronic kidney disease.
Authors and Affiliations
Cherekar L N, Hazari N R
Keywords
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