Uric acid in men with acute stroke

Abstract

Higher levels of uric acid in men as compared to women can be a reason behind greater incidence of stroke in men. The objective of the present study was to evaluate the levels of uric acid in men with acute stroke and correlate with stroke severity.For the purpose of the study ,50 male patients of acute stroke admitted to the hospital and 50 age matched healthy controls were included in the study. Routine biochemical parameters including fasting blood glucose, uric acid and lipid profile were assessed in serum obtained from 5 ml of fasting blood sample. Patients with kidney or liver diseases, malignancies, diuretic use, alcohol intake, on iron or antioxidant therapy were excluded from the study. Initial stroke severity was measured by the National Institute of Health Stroke (NIHS) scale. It was found that , among the 50 cases, 38(76%) had ischemic stroke and 12(24%) had hemorrhagic stroke. Serum uric acid levels were very significantly higher in cases (p<0.001) than controls. There was strong positive correlation between uric acid levels and initial stroke severity (p=0.006, r=0.386). Also, serum uric acid showed a statistically significant correlation with fasting blood glucose, TG and VLDL and an inverse association with HDL in both cases and controls. The conclusion drawn was that the significantly higher levels of uric acid in men with stroke and the positive association of uric acid with stroke severity suggest a possible role of uric acid as a risk factor for stroke in men.

Authors and Affiliations

Bhadra J, Mahor DS, Seth S, Ghalaut VS, Dhupper V, Kulshrestha MR

Keywords

Related Articles

Insurgency in Nagaland: An Impediment to Economic Development

Considering its strategic geographical location and abundant natural resources, Nagaland is also one among the other Northeast states of India that holds for a promising economic development. However, economic developme...

Documentation of Aquatic Invasive Alien flora of Jammu region, Jammu and Kashmir

The present study deals with the first ever inventorisation and documentation of aquatic invasive alien plant species of Jammu region with background information on family, habit and nativity . Total 55 invasive alien p...

Optimization of Production of Fructooligosaccride using Aureobasidium pullullans

This present study focuses on the microbial production of Fructosyl Transferase (FTase) and the production of Fructooligosaccharides(FOS) by transfructosylation using this enzyme. Fructooligosaccharides are industrially...

Friends Or Enemies? An Evaluation of The Relationship Between Rising Hegemonies And Established Hegemonies In International Relations

There are some who see China‘s sudden rise to the position of power and influence on the globe as a threat to their position and place in world economy. Current trends in world politics however reveals that the quest to...

Women Empowerment Through Higher Education

India holds the second position in the world of having highest population. There are approximately 49% female in total population of it. But if we analyze the current status of Indian women with other countries of the w...

Download PDF file
  • EP ID EP30898
  • DOI -
  • Views 252
  • Downloads 0

How To Cite

Bhadra J, Mahor DS, Seth S, Ghalaut VS, Dhupper V, Kulshrestha MR (2015). Uric acid in men with acute stroke. International Journal of Interdisciplinary and Multidisciplinary Studies (IJIMS), 2(5), -. https://europub.co.uk/articles/-A-30898