Urinalysis as a diagnostic tool for febrile urinary tract infection in children aged 2 months - 2 years
Journal Title: Paediatrica Indonesiana - Year 2014, Vol 54, Issue 2
Abstract
Background Children aged 2 months to 2 years with febrileurinary tract infection (UTI) need special attention consideringkidney complications, unspecified symptoms, and difficult urinesample collection. Urinalysis was the main supportive examinationfor UTI because of its immediate result and widespreadavailability.Objective To estimate urine nitrite, leukocyte esterase (LE),leucocyturia, bacteriuria, and their combinations as a diagnostictool for febrile UTI in children aged 2 months to 2 years.Methods This is a diagnostic study held in Cipto MangunkusumoHospital, Tangerang General Hospital, Fatmawati Hospital, andBudhi Asih Hospital, involving 7 5 children aged 2 months to 2years. Urine samples for urinalysis and urine culture were collectedusing urine collector in all subjects. Clinical pathologists whoperformed urine culture, did not know the results of urinalysis.Results By parallel test analyses, we found that the best diagnosticvalue was the combination of 3 tests (LE, leucocyturia, andbacteriuria). This combination test showed sensitivity, specificity,positive predictive value (PPV), negative predictive value (NPV),positive likelihood ratio (LR+), and negative likelihood ratio(LR-) of 69%, 95%, 85%, 88%, 13.1, and 0.3.Conclusion The combination test of LE, leucocyturia, andbacteriuria shows high specificity, NPV, and LR+ . Therefore, thenegative results of these 3 tests in combination can be used to ruleout UTI.
Authors and Affiliations
Ayijati Khairina, Partini Trihono, Zakiudin Munasir
Keywords
Related Articles
- EP ID EP458710
- DOI 10.14238/pi54.2.2014.100-8
- Views 90
- Downloads 0
Forced expiratory volume in 1-second and blood gas analysis in children during asthma attacks
Background Asthma is the most common chronic disease in the world, with a high incidence in children. Blood gas analysis and pulmonary function test using spirometry are recommended to evaluate the degree of asthma in ch...
Effect of calcium and vitamin D supplementation on serum calcium level in children with idiopathic nephrotic syndrome
Background Patients with idiopathic nephrotic syndrome (NS) maydevelop hypocalcemia caused by low levels of albumin and vitaminD -binding protein, which subsequently decreases calcium absorptionin the intestine. Hypocalc...
Cow’s milk exposure and atopic dermatitis after six months of age
Background About 60% of individuals with atopic dermatitis (AD) develop their first manifestation during infancy. Cow’s milk (CM) exposure is considered to be a risk factor for AD.Objective To evaluate for an association...
Relationship between small for gestational age and aortic intima-media thickness in newborns
Background Small for gestational age (SGA) has been associatedwith adult cardiovascular disease. Small for gestational agenewborns may undergo early aortic wall intima-media thickening(aIMT) in utero.Objective To determi...
Association between specific language impairment and behavioral disorders among preschool children
BackgroundSpecific language impairment (SU) is the mostcommon developmental disorder in preschool children, causingserious impairmentE on behavioral development. To date, there havebeen few studies on SU and behavioral d...