Use and Misuse of Epidermal Nerve Fiber Density for Assessment and Treatment of Peripheral Nerve Function and Dysfunction
Journal Title: Indian Journal of Anatomy - Year 2017, Vol 6, Issue 2
Abstract
Pathoanatomical examination procedures such as epidermal nerve fiber density (ENFD) was indicative of small-fiber dysfunction and the objective of this short communication was to throw light on ENFD and its use in assessment and treatment of peripheral neuropathies. Limited yet sufficient evidence shows that ENFD had established normative reference range, predictive equation with respect to age and gender, low inter-measurement variability; and was correlated to quantitative sensory test measures, morphometry, pain-related evoked potentials and C-fiber axon reflex flare size; was used in HIV-related peripheral neuropathy, sensory ganglionopathiesand Diabetic peripheral neuropathy; and, was influenced by topical treatments such as capsaicin and lidocaine patches. Thus ENFD is the one of earliest indicator of nerve function and dysfunction in peripheral nerve disorders.
Authors and Affiliations
Senthil P. Kumar
Keywords
Related Articles
- EP ID EP467819
- DOI 10.21088/ija.2320.0022.6217.31
- Views 61
- Downloads 0
Incidence of Congenital Anomalies of Urinary Tract in Patients with Dysuria in South Maharashtra Population
One hundred and five patients (81 males and 24 females) with symptoms of dysuria associated with urinary tract infections, reflux of urine, urinary stasis were studied at MIMSR Medical College and YCR Hospital, Latur, fr...
Study of Anatomical Variations of Temporal Bone Using High Resolution Computed Tomography of Temporal Bone
Background and objective: High Resolution Computed Tomography (HRCT), a modification of routine Computed Tomography, provides a direct visual window into the temporal bone providing minute structural details. Purpose of...
A Study on Foramen Magnum Morphometry in 3-Dimensional CT Scans and Dry Skulls and its Neurosurgical and Forensic Implications
Background: A study on foramen magnum morphometry has immense neurosurgical and forensic implications due to its association with myriad intracranial tumours and sexual dimorphism. Aims and Objectives: To study dimension...
Accessory Renal Arteries: A Cadaveric Study of 144 Kidneys
Background: Accessory renal arteries are one of the most commonly seen variation of renal arteries. Hilar, upper polar and lower polar are the types of accessory renal arteries seen. Aim: To find the incidence of various...
Morphometric Study of Tricuspid Valve Annulus and Right Ventricular Papillary Muscle: A Cadaveric Study from Marathwada Region
Tricuspid valve complex is commonly involved in various heart diseases like rheumatic heart diseases, congenital cardiac anomalies etc. Studies on Tricuspid valve complex, in Maharashtrians are few; so the present work w...