USE OF CYCLOPLEGIC AND MYDRIATIC AMONG SUCCESSFUL POSTDACRYOCYSTORHINOSTOMY CASES: HOW SAFE IT IS!!
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2019, Vol 6, Issue 23
Abstract
BACKGROUND In post dacryocystorhinostomy patients, absorption of topical drugs is higher due to exposed nasal mucosa. As a result, systemic side effects are more common than local effects. So, ophthalmologists must be aware of the dangers of ocular and systemic side effects of these combined drugs especially in patients with cardiovascular, renal and other morbidities which are sometimes really challenging. The main purpose of the study is to assess the safety of giving a mixture containing 0.75% tropicamide and 2.5% phenylephrine among the successful post DCR cases in normotensive and hypertensive patients, to find out whether shortening of the nasolacrimal passage which occurred after DCR surgery has any effect on the absorption and systemic effects of ocular drops and record the difference of these complications (local and systemic) in pre- and post-operative DCR sides with that of the normal sides. METHODS Fifty patients of successful post dacryocystorhinostomy cases were studied between February 2018 and January 2019. On admission, pupillary diameter, pulse rate, blood pressure, ECG changes were measured before and after application of drops and same procedures were done one and half month after DCR operation. This is a non-randomized control trial designed to determine the safety of use of cycloplegic and mydriatic among the successful post dacryocystorhinostomy cases. RESULTS The size of pupillary diameter was less in post DCR side compare to control side (p=0.000). Both blood pressure (p=<0.05) and pulse rate changes were also seen but pulse rate changes was statistically insignificant (p=0.302). Significant ECG changes were seen in hypertensive patients. CONCLUSIONS Removal of obstruction and shortening of nasolacrimal passage by DCR surgery causes alteration of transportation and absorption of drugs. So, before its application, pharmacodynamics and systemic adverse effects of applied drugs should be kept in mind.
Authors and Affiliations
Santanu Sinha Babu
Keywords
Related Articles
- EP ID EP667302
- DOI 10.18410/jebmh/2019/330
- Views 97
- Downloads 0
A STUDY ON NEONATAL SEIZURE AMONG INTENSIVE CARE ADMITTED NEWBORNS AT TERTIARY CARE CENTRE, KUPPAM
BACKGROUND Neonatal seizures typically depict a significant underlying neurological disease. The recognition of aetiology and clinical profile for neonatal seizure is often helpful with respect to prognosis and treatment...
CERVICAL EPIDURAL BLOCK AS AN ALTERNATIVE TO GENERAL ANESTHESIA IN A PATIENT WITH ANTICIPATED DIFFICULT AIRWAY AND DERANGED THYROID FUNCTION FOR THYROID SURGERIES
Choosing safe anesthetic technique is pivotal role for anesthesiologist. It depends Age, preexisting systemic diseases and Type of surgery. In this case report we have chosen Cervical Epidural Block as an alternative to...
COMPARATIVE STUDY ON SAFETY AND EFFICACY OF MISOPROSTOL AND DINOPROSTONE IN CERVICAL RIPENING AND LABOUR INDUCTION
BACKGROUND Induction of labour is the process of initiation of uterine contractions for the purpose of vaginal delivery. Use of prostaglandins in induction of labour improves the obstetric outcomes in complicated cases s...
ROLE OF FIBEROPTIC BRONCHOSCOPY IN PATIENTS WITH SPUTUM SMEAR NEGATIVE FOR ACID FAST BACILLI AND CHEST XRAY SUGGESTIVE OF PULMONARY TUBERCULOSIS
AIMS: To study the role of fiberoptic bronchoscopy in patients with sputum smear negative for AFB and chest X-ray suggestive of pulmonary tuberculosis. SETTINGS AND DESIGN: After informed consent, 60 adult patients with...
EUSTACHIAN TUBE: ITS FUNCTIONS AND DYSFUNCTIONS IN RELATION TO THE PATHOGENESIS OF MIDDLE EAR
Knowledge of developmental anatomy and physiology of Eustachian tube provides evidence that most infants and young children will have fewer episodes of otitis media as the age advances, thus aggressive measures are not w...