USE OF ECG AND OTHER CLINICAL VARIABLES FOR DETECTING PULMONARY HYPERTENSION IN COPD PATIENTS- A CROSS-SECTIONAL OBSERVATIONAL STUDY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 2
Abstract
BACKGROUND Chronic Obstructive Pulmonary Disease (COPD) has emerged as a leading cause of mortality worldwide. Pulmonary Hypertension (PH) is a frequent complication associated with COPD and it is prevalent among 10% - 30% of the COPD patients with moderateto-severe disease. However, PH-associated with COPD is poorly diagnosed due to the lack of specific clinical investigations and sensitive markers. Despite being the most common techniques, the use of non-invasive techniques like echocardiography and electrocardiography for diagnosing PH in COPD is controversial. MATERIALS AND METHODS The cross-sectional observational study was conducted for a period of two years in a super speciality hospital in south India. The subjects were classified based on the status of PH. Apart from routine laboratory investigations, pulmonary function test, transthoracic 2D-echo with colour Doppler and electrocardiography were performed for all the participants. Different clinical and demographic variables were compared between COPD subjects with and without PH and their significance were studied. RESULTS The study included a total of 44 subjects with a mean age of 61.3 ± 10.84. PH was detected in 11 subjects based on the 2D ECHO Doppler findings. On comparison of the various ECG findings between the two groups, only P axis > 600 (P= 0.0336) showed a significant variation and V1-R/ S > 1 (0.0507) showed a trend towards significance. CONCLUSION ECG may not be an accurate non-invasive tool for diagnosing PH in COPD patients.
Authors and Affiliations
Asha Rangadham, Varun Dasegowdanapalya Gangaiah
Keywords
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- EP ID EP284541
- DOI 10.14260/jemds/2018/37
- Views 75
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