Use of Gabapentin as an Adjunct Agent in the Treatment of Neonatal Abstinence Syndrome: A Case Report
Journal Title: International Journal of Medical and Pharmaceutical Case Reports - Year 2015, Vol 3, Issue 4
Abstract
We report the use of Gabapentin (Neurontin), an anticonvulsant and analgesic, as a non-opioid adjunct agent in the treatment of a term newborn infant with neonatal abstinence syndrome (NAS). Initial treatment with methadone to prevent withdrawal symptoms was not fully effective. Despite the addition of clonidine, an alpha-2 agonist, he was still unable to be weaned off opioids. The addition of gabapentin reduced symptoms, allowing for successful taper off methadone, and discharge from the hospital. As a non-opioid agent, gabapentin is a drug with potential for assisting with the difficult task of treating NAS refractory to standard opioid therapy due to its sedative and analgesic properties without any respiratory depression.
Authors and Affiliations
Alyssa Brzenski, Mark Greenberg
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