Use of Lactobacillus Acidophilus R0052 and Lactobacillus Rhamnosus R0011 Probiotic Strains in Children with Burn Injuries
Journal Title: Гастроентерологія - Year 2016, Vol 4, Issue 62
Abstract
Today, burn injury is second most frequent diagnosis in all children hospitalized with injuries. The main cause of death in cases of extensive deep burns is burn infection that occurs in 23 to 82 % of all burn units’ patients. Antibacterial treatment rationality is of great importance in fighting the generalized infections. This paper is aimed at scrutinizing the incidence and course characteristics of the antibiotic-associated diarrhea (AAD) in burn patients, as well as the possibility of its prevention in children receiving antibacterial treatment in the Regional Burn Unit of Zaporizhzhia. During 2012–2015, we have observed 438 children with burn injuries, who received antibiotics. We observed children receiving antibiotics and examined over hospitalization time by detection of the highly specific for antibiotic-associated diarrhea A + B Clostridium difficile toxins in stool, which allowed diagnosing the enterocolitis due to Clostridium difficile associated with antibiotics administration (A4.07, ICD‑10). AAD prevention methods have been developed, among which preventive (from the first hours of hospitalization) administration of oral probiotic agent containing Lactobacillus acidophilus R0052 and Lactobacillus rhamnosus R0011 probiotic strains as a part of the Lacidofil® preparation dosed by age should be considered a major one. Prophylactic prescription of probiotic strains with antitoxic action against Clostridium difficile had reduced the incidence of antibiotic-associated diarrhea in children and the severity of its symptoms by 3.4 times.
Authors and Affiliations
M. V. Patsera, Ya. S. Skrypnykova, O. H. Ivan’ko
Keywords
Related Articles
- EP ID EP210250
- DOI 10.22141/2308-2097.4.62.2016.81095
- Views 117
- Downloads 0
Portal Hypertensive Gastropathy (Literature Review)
The article is dedicated to portal hypertensive gastropathy (PHG) — a secondary change of the mucousal and submucosal layer of the stomach on the background of liver cirrhosis (LC) of any origin etiology and concomitant...
Hemodynamic Changes in Patients with Chronic Pancreatitis on the Background of Coronary Heart Disease
The analysis of the survey results in 120 patients with chronic pancreatitis and coronary heart disease was conducted. Along with the standard examination, these patients underwent Doppler imaging of the abdominal aorta...
Zemstvo Doctor and Dramatist
The study of the life and professional activity of Hryhorii Maksymovych Borakovskyi (1846–?), zemstvo doctor, doctor of medicine, forensic expert, public figure, writer, extraordinary personality, has been carried out. H...
Using the Quantitative Determination of HbsAg to Monitor Antiviral Therapy of Chronic HBV-Infection
Currently, the main unresolved issue in monitoring antiviral therapy of chronic HBV-infection is the lack of clear predictors of sustained virologic response to treatment. These predictors would allow early identificatio...
Clinical and pathogenetic aspects of chronic pancreatitis in conjunction with autonomic dysfunction
Background. The article analyzes the features of the state of the autonomic nervous system in patients with chronic pancreatitis (CP). Studies have shown that the presence of autonomic dysfunction (AD) complicates the co...