Use of Meter Dose Inhaler (MDI) Corticosteroid Therapy, May Cause Tuberculosis, in Patients with Bronchial Asthma
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 12
Abstract
The aim of present study was to evaluate the incidence and pattern of tuberculosis in Bronchial asthma patients receiving inhalational corticosteroid therapy by MDI. Materials and Method: A total of 76 patients taking MDI steroid for bronchial asthma, and 76 patients suffering from the similar disease but not receiving MDI steroids serves as a control, were included in the study and evaluate for the incidence and pattern of tuberculosis. All the patients were followed up for 18 months. Results: Out of 76 patients, 4 patients (5.26%) receiving MDI steroid developed tuberculosis as against patients not receiving MDI steroid, out of 4 patients, who developed tuberculosis, one developed sputum smear positive pulmonary disease, one had sputum smear negative disease and two had extra pulmonary tuberculosis in the form of pleural effusion and tubercular lymphadenitis one each. All patients were treated with standard anti tuberculous therapy using RNTCP guidelines and all patients recovered from the disease. Conclusion: Inhalational corticosteroid in the form of MDI causes a significant increase in incidence of tuberculosis.
Authors and Affiliations
Dr Gaurav Tiwari
Keywords
Related Articles
- EP ID EP500123
- DOI -
- Views 81
- Downloads 0
A Rare Case of Invasive Mole with Silent Uterine PerforationA Case Report
Invasive mole is a condition where the trophoblastic tumour invades the myometrium that may erode into the uterine vessels, causing massive intraperitoneal haemorrhage. Normally it gets detected by ultrasonography, confi...
Laterally Displaced Flap – A Case Report
Gingival recession may cause the patient to feel esthetic discomfort and dentin hypersensitivity. Obtaining predictable and esthetic root coverage has become an important goal of a periodontal surgeon. Even though there...
Self Harm / DSH Episodes in BPAD – Study in a Rural Setup
Patients with Bipolar disorder have high rates of medical, psychiatric and substance abuse disorders which contribute to self harm, reduced life expectancy and decreased quality of life. Lithium effective treatment was a...
Ox tail post traumatic Nocardial Keratitis Rare Case Report
This is rare case report of unexpected sudden accidental Ox tail trauma, to the eye which gives corneal abrasion along with epithelial defects, superficial Infiltration develops in a ring like wreath pattern which is typ...
Post-Partum Hemorrhage- What is the Vital Back up in a Government Tertiary Care Institution
Severe Obstetric hemorrhage is the most dreaded obstetric emergency. The most common type of obstetric hemorrhage is post-partum hemorrhage (PPH). PPH remains a foremost cause of maternal mortality and morbidity worldwid...