Use of oral vs vaginal Misoprost following mifepristone(200mg) for second trimester abortion
Journal Title: Medpulse International Journal of Gynaecology - Year 2019, Vol 9, Issue 2
Abstract
Background: Various medical methods for second trimester medical termination of pregnancy exist, which includes misoprostol alone oral or vaginal and combination of both mifepristone and misoprostol. Misoprostol following mifepristone can be given both vaginally and orally. this study is a comparison between oral and vaginal route of misoprostol after cervical priming with mifepristone. Method: this was a prospective comparative study of mifepristone(200mg) +oral misoprostol and mifepristone(200mg) +vaginal misoprostol for second trimester MTP(14 -20weeks).20 patients received mifepristone (200mg) followed by oral misoprostol(400mcg) and 20 patients received mifepristone(200mg) followed by vaginal misoprostol(400mcg).upto a maximum of three doses of misoprostol were used. in both groups oxytocin infusion were started if abortion did not occur. efficacy of oral versus vaginal misoprotol, induction-abortion interval and need for surgical intervention were analysed. Results: both groups were well matched in terms of age, parity, mean gestational age and indication for MTP. the overall induction abortion interval in group A(oral misoprostol) was 10.6 hours where as it was 8.23 hours in group B(vaginal misoprostol).complete abortion was achieved in almost 100% cases. only 3 case required check curettage for retained product as diagnosed by ultrasonography. Conclusion: though both oral and vaginal misoprostol are effective and safe method of abortion. vaginal route appears to be more efficacious for 2nd trimester.
Authors and Affiliations
Geeta Rani, Sachin Kuimar Singh, Usha Kumari, Anupama Sinha
Keywords
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- EP ID EP470354
- DOI 10.26611/1012924
- Views 172
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