Use of topical dorzolamide in a patient with X-linked juvenile retinoschisis
Journal Title: Scholars Journal of Medical Case Reports - Year 2017, Vol 5, Issue 2
Abstract
Abstract: We present a patient with X-linked juvenile retinoschisis before and after a topical use of dorzolamide. Ophthalmologic examinations showed a best corrected visual acuity (BCVA) of 0.3 in the right eye and 0.5 in the left eye. Fundoscopy demonstrated the typical stellate maculopathy of radiating cystoid spaces. Moreover, optical coherence tomography (OCT) results revealed a cleavage of the retina with thin-walled, vertical palisades separated by low reflective cystoid spaces. The patient was instructed to apply 2% dorzolamide three times daily in each eye. During a 3-month treatment period, OCT revealed a marked improvement in the foveal cystic lesions in the right eye, but not in the left eye. Moreover, BCVA was 0.6 in the right eye and 0.5 in the left eye after the 3-month treatment with dorzolamide. Our findings suggest that topical dorzolamide have some effect on improving foveal cystic lesions but it does not improve BCVA significantly. Keywords: X-linked juvenile retinoschisis, optical coherence tomography, carbonic anhydrase inhibitors, dorzolamide.
Authors and Affiliations
Shinji Makino
Keywords
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