Use of Vacuum Therapy in the Treatment of Wounds in Patients with Diabetic Foot Syndrome

Abstract

Introduction. Acute and chronic wound defects of the lower extremities occurs in 15–25 % of patients with diabetes mellitus, serving as the direct cause of frequent amputations of lower extremities in 12 % of patients. One of the current and promising directions of wound healing is vacuum therapy. Objective. To study the effect of vacuum therapy on the course of acute and chronic wound process in patients with diabetic foot syndrome, depending on the pathogenic form of the injury, and on the basis of the findings to improve the outcomes of surgical treatment of the above-mentioned pathology. Materials and methods. The study involved 239 patients with complicated forms of diabetic foot syndrome. Monitoring of the wound progress is complemented by clinical, cytological, microbiological and morphological criteria. In the treatment of patients, we have used vacuum therapy device by Agat-Dnepr company. Vacuum therapy of wounds was carried out in the modes of negative pressure within 80–125 mmHg. Results. On the 2nd — 3rd day of vacuum treatment, there was a significant decrease of local manifestations of acute inflammation. At the same time, we have noted a significantly reduction in the amount of wound defects. There were positive changes from the side of wound microbial contamination defects. Application of continuous vacuum therapy in the treatment of wound defects greatly improved the performance of local microcirculation. Conclusions. Use of vacuum therapy in the combination treatment of acute and chronic wounds in patients with diabetic foot syndrome has a local and systemic action that enables to stabilize the course of wound process, to stimulate regenerative processes, to eliminate manifestations of endogenous intoxication and violations of immunological reactivity.

Authors and Affiliations

P. O. Herasymchuk, I. M. Deikalo, V. H. Vlasenko, D. B. Fira, A. V. Pavlyshyn

Keywords

Related Articles

Peculiarities of Lipid Metabolism in Patients with Prolactinomas during Suppressive Dopamine Agonist Therapy

The article presents the data of lipid metabolism at the stages of long-term (12 months) suppressive therapy with dopamine agonist cabergoline in 61 patients with prolactinoma. It is proved that the normalization of prol...

Micronutrient Imbalance in Diffuse Focal Form of Autoimmune Thyroiditis

The levels of selenium and cadmium in the hair of women living at least ten years in the city of Kharkiv have been studied. We have analyzed data in the groups with autoimmune thyroiditis (AIT) and without thyroid pathol...

Safety and Efficacy of Hypoglycemic Therapy: Place of Metformin

This review describes results of some basic large clinical trials on glucose lowering therapy directed on a prevention of macro- and microvascular complications of diabetes mellitus type 2. Authors emphasize that the res...

Primary Hyperparathyroidism: Etiology, Pathogenesis, Clinical Picture, Diagnosis, Treatment, Quality of Life (Review of Literature)

The author provide a literature review of the data for the last 10–15 years on the problem of primary hyperparathyroidism (PHPT). PHPT was first described in 1943, but interest to the diseases of the parathyroid glands g...

Influence of nutrient correction on adiponectin circulating level and cardiovascular risk factors in patients with type 2 diabetes mellitus and non-alcoholic fatty liver disease

Aim — to evaluate the influence of dietary recommendations on adiponectin circulating level and haemodynamic characteristics in patients with type 2 diabetes mellitus (DM) and non-alcoholic fatty liver disease. Materials...

Download PDF file
  • EP ID EP206917
  • DOI -
  • Views 81
  • Downloads 0

How To Cite

P. O. Herasymchuk, I. M. Deikalo, V. H. Vlasenko, D. B. Fira, A. V. Pavlyshyn (2016). Use of Vacuum Therapy in the Treatment of Wounds in Patients with Diabetic Foot Syndrome. Міжнародний ендокринологічний журнал, 2(74), 124-129. https://europub.co.uk/articles/-A-206917