Usefulness of Eosinophil-Lymphocyte Ratio to Predict Stent Restenosis
Journal Title: Dicle Tıp Dergisi - Year 2016, Vol 43, Issue 2
Abstract
Objective: Stent restenosis (SR) is an important complication of percutaneous coronary intervention. There are many studies explored the relation of eosinophils with SR, however, there is no data about relationship between eosinophil-lymphocyte ratio (ELR) and SR. In this study we aimed to investigate the relationship between the value of ELR on admission and SR. Methods: The study was included 314 patients who had been applied a coronary stent implantation and they were admitted to cardiology clinic with stabile angina and underwent repeat coronary angiography. The data obtained from patients were analyzed retrospectively. The patient group was consisted of 197 patients who were diagnosed as SR, and the control group was consisted of 117 patients whose stents were patent angiographically. Results: The groups were similar in terms of age, gender, hypertension, diabetes mellitus, LDL-C, HDL-C, platelet count, platelet-lymphocyte ratio (PLR), hemoglobin and left ventricle ejection fraction (LVEF). White blood cell (WBC), neutrophil, eosinophil, C-reactive protein (CRP), ELR and neutrophil-lymphocyte ratio (NLR) on admission were higher in the SR group compared to the controls. All patients were categorized into two groups according to ELR values and SR was more frequent in the high ELR group compared to low ELR group. An ELR value of ≥0.745 predicted SR with 64% sensitivity and 61% specifity. Conclusion: In this study ELR was found statistically higher in SR patients compared to the controls. According to our data ELR as an inexpensive and easy method, may contribute to determination of high risk patients and increased ELR can be used as a predictor of SR. Key words: Coronary restenosis, stents, eosinophils, lymphocytes
Authors and Affiliations
Mehmet Bilik, Halit Acet, Murat Yüksel, Mustafa Oylumlu, Nihat Polat, Adem Aktan, Sait Alan
Keywords
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- EP ID EP138730
- DOI 10.5798/diclemedj.0921.2016.02.0685
- Views 95
- Downloads 0
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