Using Antibiotic loaded bone cement (ALBC) as the novel method to treatment of chronic osteomyelitis
Journal Title: Scholars Journal of Medical Case Reports - Year 2016, Vol 4, Issue 12
Abstract
Bone and joint infection is the main complication of bone fracture as a result of pyogenic bacteria. The long-term clinical course, extended period of silence, cases of recurrence and abundant discharge are the overriding side effects of bone infection that can be considered a challenge to treat the patients. Given the associated problems of bone infection, the aim of current study is to elucidate the efficiency of Antibiotic loaded bone cement (ALBC) as the novel method to treatment of chronic osteomyelitis. This study looks at the treatment of chronic osteomyelitis through cement containing antibiotic approach. Five patients with chronic osteomyelitis as a consequence of surgical operation of bone fracture were evaluated for efficiency of ALBC method (Gentamicin and Vancomycin have been used as antibiotics in our homemade bone cement). The study was performed in Imam Khomeini hospital of Falavarjan in Isfahan between February 2009 to January 2014. The patient information was obtained from the hospital data bank to monitor treatment and recovery. The ALBC application in temporary manner leads to magnificent results about treatment of chronic osteomyelitis and septic arthritis. However, extensive and complete debridement of necrosis and infectious area with application of proper fixation and bone graft should be considered with the ALBC. Our results have shown that antibiotic loaded cement leads to reduction of pyrogenic discharge as the main clinical complication of chronic osteomyelitis in all patients also; the application of extensive debridement and antibiotic drugs is declined. It should be noted that the patient satisfaction was increased by this approach. Finally, the cement-containing antibiotic can be suitable approach to reduce bone infection. Keywords: Cement-containing Antibiotic, Chronic Osteomyelitis, Bone Fracture.
Authors and Affiliations
Reza Babaei, Hooman Shariatzadeh
Keywords
Related Articles
- EP ID EP374291
- DOI -
- Views 82
- Downloads 0
Leiomyoma of Tunica Aluginea: A Case Report
Leiomyomas are benign tumors arising from any site containing smooth muscle. They are infrequently found in the genitourinary tract,most common site here being renal capsule. Rarely they may found in the epididymis ,sper...
Epidermal Inclusion Cyst In Palatine Tonsil: A Case Report
Dermoid cysts are squamous epithelium lined cysts commonly found in head and neck region. Dermoid cyst arising in the pharynx is very rare. It presents in the early infancy or childhood as an unilateral mass arising from...
Bilateral Nephroblastoma & Nephroblastomatosis (About 2 Cases)
The nephroblastomatosis is defined by the presence of multiple or diffuse nephrogenic remains, regarded as precursor’s nephroblastoma and appear in up to 90% of bilateral Wilms, nephroblastoma is the first renal tumor of...
Meckel Gruber Syndrome-An Autopsy Report of a Rare Case
Abstract:Meckel Gruber Syndrome is a rare autosomal recessive disorder characterized by a typical clinical triad of meningo-encephalocele, polycystic kidneys and polydactyly. The worldwide incidence varies from 1 in 1325...
Accidental Diagnosis of Alkaptonuria in a Suspected Case of Mucopolysaccharidosis
Alkaptonuria is a very rare genetic disorder characterized by the lack of enzyme homogentisate oxidase in tyrosine metabolism. This leads to the accumulation of homogentisic acid in cells and body fluids. The clinical fe...