Using ultra-rapid insulin analogs in children and adolescents with type 1 diabetes mellitus
Journal Title: Міжнародний ендокринологічний журнал - Year 2017, Vol 13, Issue 8
Abstract
Background. The purpose of the study was a retrospective comparative analysis of using insulin analogues of the prolonged and ultra-short action and human genetically engineered insulins of middle and short action in children and adolescents with type 1 diabetes mellitus (DM). Materials and methods. The influence of ultra-rapid insulin analog in comparison with human rapid-action insulin on the course of type 1 DM in 100 children and adolescents was studied. It was applied as basal-bolus regimen of insulin therapy. Analysis of parameters which reflect criteria of insulin therapy effectiveness, positive effect of ultra-rapid insulin analog on the course of DM has been performed. Results. Application of ultra-rapid insulin analog before each meal improved parameters of pre- and postprandial glycemia, decreased the range of fluctuations of blood sugar during the day, reduced and maintained HbA1c level without augmentation of frequency and intensity of hypoglycaemia, and also decreased the level of noctural hypoglycaemia. Conclusions. The ultra-rapid insulin analog is the drug of choice for the effective use in insulin pumps.
Authors and Affiliations
О. V. Bolshova, N. A. Sprinchuk
Keywords
Related Articles
- EP ID EP264349
- DOI 10.22141/2224-0721.13.8.2017.119273
- Views 50
- Downloads 0
Features of carbohydrate metabolism in women of early reproductive age with polycystic ovary syndrome
Background. Fertility of women, especially with an endocrine hyperandrogenic imbalance, requires special attention, as incidence of reproductive losses in this group reaches almost 67 %. The objective is to determine the...
Diabetes Mellitus: New Views and Old Delusions. Part 2. Pevention of Diabetes Mellitus Type 2
No abstract
Citoflavin® In Discirculatory Encephalopathy Treatment of Type 2 Diabetic Patients: Experience of Use
Results of Cytoflavin® use for the treatment of dyscirculatory encephalopathy in type 2 diabetic 42 patients are described in this article.
Impact of Gender and Age Factors on the Correlation of Pituitary-Thyroid Hormones in Patients with Autoimmune Thyroiditis
In 292 patients with autoimmune thyroiditis, indicators of thyroid homeostasis were studied by levels of thyroid stimulating hormone (TSH), T3, T4, FT4, as well as their ratio in groups of men and women under the age of...
Expression of mRNA IL-1β, IL-17А and IL-10 of oral epithelium in diabetic children
The aim of the study was to investigate the indexes of cytokines profile in the epithelium of oral cavity of children with type 1 diabetes mellitus (DM) taking into account present metabolic violations. Materials and met...