Uterine Endometrial Sarcoma with Carcinomatosis Treated with Iterative Surgery Associated with Systemic and Intraperitoneal Chemotherapy
Journal Title: Journal of Clinical and Medical Research - Year 2020, Vol 2, Issue 5
Abstract
Introduction: Endometrial sarcoma is a rare condition, affecting women in their 60s. If total hysterectomy associated with bilateral adnexectomy is the standard treatment and can control the disease when it is localized in the uterus, at the peritoneal localization stage its prognosis becomes more negative with reduced possibilities of resection and overall survival at 5 years, therefore, the same with rates close to 30%. We report two cases of endometrial sarcoma with peritoneal localizations managed with a multidisciplinary approach and in several steps or multimodal approach associating a cytoreduction preceded or associated with systemic chemotherapy and intraperitoneal chemotherapy. These two advanced tumours were cured with this approach and at the final step, no deposit tumor were present. The global survival is respectively of 28 months and 63 months. Conclusion: this approach seems to be efficient in front of the advanced stage of endometrial sarcoma and we think that it must be adopted for a great number of patients to improve the survival and quality of life.
Authors and Affiliations
Salah Berkane1*, Mustapha Kheder1, Salim Belkherchi1, Chemssedine Benkhelat1, and Youcef Mahmoudi1
Keywords
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- EP ID EP708408
- DOI https://doi.org/10.37191/Mapsci-2582-4333-2(5)-046
- Views 57
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