Utility of Carica papaya extract in treatment of chemotherapy induced thrombocytopenia in humans, experience of a tertiary care hospital in Kashmir
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH - Year 2016, Vol 8, Issue 7
Abstract
Chemotherapy is still the standard of care in management of solid tumors. Chemotherapy has a common toxicity of myelosuppression. Some chemotherapy regimens cause either thrombocytopenia or bi-cytopenia. Living in developing countries pose another challenge in treatment of myelosuppression, and to continue timely chemotherapy. Aim: To study the role of Carica Papaya extract in treatment of chemo induced thrombocytopenia in low socio-economic strata of patients. Methods: It was a prospective study, in which patients of different solid tumors were enrolled. Haemogram of all patients was recorded when they got myelosuppression on continuation of chemotherapy. Carica Papaya plant extract in the form of capsule (Swiss count from Friska) 700 to 1400 mg a day in two divided doses was given for a period of five days. Repeat haemogram was carried out on sixth day. Results: There was median nine fold rise in platelet count and median 1.65 fold rise in total leucocyte count in cases, while as in controls; there was 4.3 fold rise in platelet count. Conclusion: This is a very economical method of treatment of chemotherapy induced myelosuppression and very much recommended for developing countries, to decrease cost of treatment significantly.
Authors and Affiliations
Javvid Muzamil, Dr. ShiekhAejaz Aziz, Dr. Gull Mohammad Bhat, Dr. Abdul Rashid Lone, Dr. AnsarHakim, Dr. NadeemShouket, Dr. Burhan Wani, Firdousa Nabi
Keywords
Related Articles
- EP ID EP405109
- DOI -
- Views 113
- Downloads 0
Ectrodactyly: the ‘lobster claw’ anomaly – rare report of an indian family demonstrating autosomal dominant inherittance pattern
Ectrodactyly [Split hand/foot malformation (SHFM) or cleft hand or claw hand or lobster anomaly or central ray deficiency] is a limb malformation involving central rays of autopod and presenting with median clefts of ha...
Ovarian hyperstimulation syndrome (ohss) following a natural conception, a case report and review of literature
Introduction: OHSS is a rare complication occurs following the use of assisted reproductive technologies. Most of the current literature describes spontaneous OHSS in patients with endocrine disorders, pregnancy with tri...
Correlation of severity of pulmonary regurgitation with right ventricular diastolic function in early post operative period in patients of tatralogy of fallot after total correction
Objective: To assess the occurrence of pulmonary regurgitation and right ventricular diastolic dysfunction in Tetralogy of Fallot after total correction and to correlate its severity with right ventricular diastolic dy...
Role of Phytoestrogens as an alternative to hormone replacement therapy in postmenopausal women
Menopause is characterized by rapid and progressive reduction in estradiol which brings about physiological and psychological changes in a woman’s life. It is estimated that in 1998, there were over 477 million postmenop...
Post operative nausea vomiting (ponv): effect of ondansetron and palonosetron
The most common and distressing symptom following general anaesthesia are nausea and vomitting which occurs in post operative period of 20% to 30% of patients. The aim of this study is to compare the anti emetic eficacy...