Utility of Fine Needle Aspiration Cytology as a Low Cost Diagnostic Tool in the Diagnosis of Cervical Lymphadenopathy- An Institutional Based Study
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 11
Abstract
Abstract: To observe the cytomorphological patterns in patients presenting with enlarged cervical lymph nodes, diagnosed by fine needle aspiration cytology (FNAC); their distribution with respect to age and gender; and to determine the accuracy of FNAC as a diagnostic procedure in cases of cervical lymphadenopathy. Out of all patients presenting with cervical lymphadenopathy from June 2017 to June 2018, in the Department of Pathology, Index medical college, Indore, Madhya Pradesh, 100 consecutive cases were enrolled in this study, following exclusion of all cases where FNAC smears were inadequate or suboptimal for diagnostic interpretation. Histopathological examination was conducted on small excision biopsy specimens / radical neck dissection where ever possible and diagnostic efficacy of FNAC was evaluated. Overall age range of the enrolled patients, presenting with cervical lymph nodes was 1 to 72 years, mean age being 35.7 years with male-female ratio, 1.6:1. Out of 100 cases, benign and malignant lesions comprised 77 and 23 cases, respectively. Most common Benign lesion was reactive hyperplasia (29%), while squamous cell carcinoma was the most common malignant lesion. The overall sensitivity, specificity, positive predictive value, negative predictive value & the diagnostic accuracy was 100%, 91.67%, 92%, 100% and 95.7% respectively. FNAC in the diagnoses of inflammatory and neoplastic diseases serves as a reliable, low cost, rapid diagnostic tool of reasonably good accuracy that can influence patient management in terms of early diagnoses, initiation of medical intervention and prevention of unnecessary surgery in patients.
Authors and Affiliations
Dr. Pranjali Sejwal, Dr. Rajesh Jaiswal
Some Hematological Parameters among Patients with Pulmonary Tuberculosis – Khartoum State
Tuberculosis is a highly prevalent chronic infectious disease caused and it’s still a common disease in develop countries and still a major cause of mortality today , can affect many part of the body like lung and bone...
Original Research article: A Study of Lipoprotein (a) and other risk factors in middle aged coronary heart disease subjects
Ischemic heart disease (IHD) is one of the most important causes of morbidity and mortality. Lipoprotein ‘a’ modulates the risk of IHD in patients with hypercholesterolemia and lipoprotein excess is commonly detected in...
Micronucleus Test as a Prognostic Marker in Cervical Lesions on Pap smear
Cervical Cancer is the third most common type of cancer among women worldwide .Micronucleus is a small additional nucleus formed due to chromosomal loss of fragmentation .Their frequency appears...
C - reactive protein as A Marker of Status of Chronic Obstructive Pulmonary Disease (COPD): A Prospective Study from PGIMS, Rohtak
Abstract: In spite of the relation between systemic inflammation and CRP in COPD, only a few studies have assessed the role of CRP in measuring the level of systemic inflammation in COPD to assess the status of disease....
Screening of Euphorbia hirta Leaves for Antipsoriatic Activity in Mice
Abstract: Psoriasis is a skin disease that causes scaling and inflammation where the skin cells grow deep in the skin and slowly rise to the surface. Worldwide nearly 1 to 3% total population affected with psoriasis. Thi...