Utility of Serial Transcranial Doppler in Diagnosis of Intracranial Vasculopathy with Computed Tomography Correlation in Children with Tuberculous Meningitis
Journal Title: Journal of Medical Science And clinical Research - Year 2019, Vol 7, Issue 1
Abstract
Background: Cerebral vasculopathy leading to infarct are the most serious complications of tuberculous meningitis (TBM). Transcranial Doppler (TCD) allows early diagnosis and monitoring of cerebral hemodynamics. It is real time, non-invasive and non-ionizing imaging modality. Aims & Objectives: 1) To describe spectrum of findings and to detect cerebral vasculopathy in pediatric TBM patients by using TCD. 2) To determine reliability of TCD by correlating its findings with computed tomography (CT) findings and stage of the disease. Materials & Methods: 40 children≤ 13 years with diagnosis of TBM referred in Department of Radiology of a Tertiary care Hospital, Rajendra Institute of Medical Sciences (RIMS), Ranchi from September 2017 – August 2018 underwent serial TCD imaging on day 1, day 3 & day 7 after obtaining written informed consent. Findings were analyzed and then compared with CT findings and stage of the disease. Results: Out of 40 study subjects who underwent TCD imaging, 19 patients showed abnormal Doppler findings in the form of stenosis in 15, vasospasm in 4, and hyperemia in 2 children. Sensitivity and Specificity of TCD as compared to CT to detect stenosis in cerebral arteries were 91.7% & 85.7% respectively. Conclusion: Serial TCD can be used as a reliable modality for early diagnosis and monitoring of intracranial vasculopathy in childhood TBM.
Authors and Affiliations
Dr Rupam Kumari
Keywords
Related Articles
- EP ID EP531542
- DOI -
- Views 96
- Downloads 0
Study of Ice Therapy in Wound Healing- Comparative Study in KMC, Katihar
Wound healing is a complex process of wound to become healthy. There is so many methods which is applied to modify the process in respect of early healing, less time consumption, better scar etc. Here we have study the e...
Antepartum Oligohydramnios and Perinatal Outcome: A Reevaluation
Objective: The study was undertaken to re-evaluate the impact of isolated oligohydramnios on pregnancy and perinatal outcome. Study Design: The study was a case-control study of 100 antenatal subjects in the Department o...
Gastric Outlet Obstruction Due to Isolated Pyloric Stenosis Following Corrosive Acid Ingestion: A Case Report
Corrosive poisoning is a common thing in children .But isolated gastric outlet obstruction after one month of asymptomatic ingestion of some unknown liquid is a rare phenomenon and rarely reported. We report a case in wh...
Seroprevalence of Hepatitis B Infection in Field Practice Area of Government Medical College, Srinagar Kashmir: A Community Based Cross-sectional Study
Hepatitis B virus infection is one of the major global public health problems with nearly 2 billion people infected worldwide, 75 % of whom are Asians. There are about 350 million chronic carriers in the world.The study...
Study of Socio-Demographic Profile and Psychiatric Morbidity among Chronic Headache Patients Visiting Tertiary Care Hospital - A Hospital Based Cross Sectional Study
Background: Headache is one of the most common human afflictions, which leads to seek medical advice. Chronic headaches markedly reduce the quality of life of the sufferers and affect all aspects of their lives. The pres...