β Sitosterol Quantification Using HPTLC in the Crude Seed Extracts for Potential Male Contraception Activity
Journal Title: Der Pharma Chemica - Year 2024, Vol 16, Issue 1
Abstract
β sitosterol is one of the main subcomponents of a group of plant sterols known as phytosterols that are very similar in composition to cholesterol. It is found to be present in many plant tissues like the leaves, roots, fruits and also seeds. These plant sterols are the active components in various pharmacological activities including anti-oxidant, anti-cancer and anti-inflammatory properties. β sitosterol, especially, has been investigated for its anti-fertility effects in the male reproductive system of mice and rats. In the present study, crude seed extracts of Carica papaya, Momordica charantia and Abrus precatorius were studied for their β sitosterol content using HPTLC technique. All of the three plants have been mentioned in several records of traditional medicine and pharmacopoeias for their various pharmacological effects including male anti-fertility activity. The confirmed presence of β sitosterol and its quantification in the crude extracts of these seeds gives us a fair idea of its involvement in their efficacy as agents of male contraception.
Authors and Affiliations
Manoshree Mondal and Devangi Chachad
Keywords
Related Articles
- EP ID EP742479
- DOI 10.4172/0975-413X.16.1.178-182
- Views 70
- Downloads 0
Requalification of Friability Testing Apparatus
Re-qualification as a part of validation is the task performed to identify or check that utilities, equipment and ancillary systems can operate within limits for their intended use. Equipment qualification is a key eleme...
Density, Ultrasonic Velocity, Viscosity and their Excess Parameters of Some Binary Liquid Mixtures of Cumene with Aromatic Hydrocarbons at 298.15 K
Density (ρ), viscosity (η) and sound velocity (u) of binary mixtures of ethyl benzene, toluene, mesitylene with cumene have been measured over the entire range of composition at temperature 298.15 K. From the experimenta...
The Effects of Bioactive Components Derived from Fruit on Different Types of Cancer: Mechanistic Pathways and Settings Associated to Stress
Background: Cancer is the world's leading cause of death today. Cancer patients' outcomes have significantly improved as surgery, radiotherapy and pharmaceuticals have advanced. Main body: fortunately the basic mechanism...
A Catalyst Free Simple and Efficient One Pot Synthesis of N-benzyloxazolidinone Derivatives
An efficient and catalyst free one pot synthesis of N-benzyloxazolidinone derivatives is developed by reaction of N-benzyl-β-amino alcohol derivatives and N, N-Carbonyldiimidazole (CDI) in DMSO. A range of novel N-benzyl...
Triazole Benzene Sulfonamides as Leads for Human Carbonic Anhydrase IX Inhibition: Updates on Research Progress
Introduction: Triazole moiety is considered as the most important heterocyclic therapeutic agent in medicinal chemistry. Identifying a lead compound or potential drug, with the requisite physical and biological character...