VALIDATED ANALYTICAL METHOD DEVELOPMENT FOR THE DETERMINATION OF MELOXICAM BY UV SPECTROSCOPY IN API AND PHARMACEUTICAL DOSAGE FORM
Journal Title: Asian Journal of Pharmaceutical Education and Research - Year 2018, Vol 7, Issue 2
Abstract
A simple, precise and specific spectroscopy method for quantitative estimation of Meloxicam in API and in pharmaceutical dosage form was developed and validated. Meloxicam showed maximum absorbance at 365 nm by using ethanol as a solvent. The linear calibration curve obeys Beer-Lambert’s law in the concentration range of (2-18µg/ml) with regression equation of curve was y=0.050x-0.005 and the correlation coefficient was found to be (R2=0.997). Validation of this method was done and applied to the estimation of Meloxicam in pharmaceutical dosage form, no interference was found in the absorbance of the drug in the presence of the common excipients and analysis conditions.
Authors and Affiliations
Meenu Chaudhary, Kiran Bhardwaj, Govinda Verma, Praveen Kumar
Keywords
Related Articles
- EP ID EP402237
- DOI -
- Views 94
- Downloads 0
VALIDATED ANALYTICAL METHOD DEVELOPMENT FOR THE DETERMINATION OF MELOXICAM BY UV SPECTROSCOPY IN API AND PHARMACEUTICAL DOSAGE FORM
A simple, precise and specific spectroscopy method for quantitative estimation of Meloxicam in API and in pharmaceutical dosage form was developed and validated. Meloxicam showed maximum absorbance at 365 nm by using eth...
SYNTHESIS, CHARACTERIZATION, ANTIMICROBIAL ANALGESIC AND ANTIINFLAMATORY ACTIVITY OF ACETOPHENONE DERIVATIVES
A novel series of mannich bases of substituted acetophenone derivatives were synthesized. These compounds were identified on the basis of melting point range, Rf values, elemental analysis, IR and 1H NMR spectral analysi...
AN OVERVIEW OF CONGESTIVE HEART FAILURE AND ITS NOVEL TREATMENT APPROACHES
Congestive heart failure (CHF) is a common clinical disorder that results in pulmonary vascular congestion with reduced cardiac output and describes the inability of the heart to meet the needs of organs and tissues for...
ANTIOXIDANT ACTIVITY OF SEED EXTRACT OF PSORALEA CORYLIFOLIA LINN.
The present study aimed to characterize the hydroalcoholic extracts prepared from seed of Psoralea corylifolia linn. The antioxidant potential of extract was evaluated using DPPH in vitro antioxidant models. This study,...
EVALUATION OF TAZAROTENE LOADED TOPICAL LIPOSOMAL GEL FOR MANAGEMENT OF ACNE
The aim was to design a liposomal delivery system for topical administration of tazarotene capable of providing controlled and localized release of the encapsulated drug in order to minimize adverse effects associated wi...