VALIDATED RP HPLC METHOD DEVELOPMENT FOR EXEMESTANE IN TABLET DOSAGE FORM
Journal Title: Journal of Drug Delivery and Therapeutics - Year 2017, Vol 7, Issue 7
Abstract
The aim of this present work was to develop stability indicating LC method, which is selective, accurate, simple, precise, reliable, cost effective and rapid for the quantification of all possible degradants and determination of exemestane. In addition, to develop and validate Stability Indicating Method for the determination of impurities (degradation products) in exemestane API by RP-HPLC. Finally, validate the developed method as per ICH guidelines.
Authors and Affiliations
Deepak Kumar Gupta
Keywords
Related Articles
- EP ID EP300606
- DOI -
- Views 86
- Downloads 0
FORMULATION DEVELOPMENT AND EVALUATION OF 5-FLUROURASIL AND ECONAZOLE GEL USING RICE BRAN WAX
Besides delivering drug to the body, a drug delivery system aims to improve patient compliance, patient acceptance. The dosage forms available for the delivery of topical agents include ointment, paste, lotion, moisturiz...
DEVELOPMENT OF CLARITHROMYCIN GASTRORETENTIVE MICROSPHERES
Gastroretentive microspheres of clarithromycin were prepared on the principle of cation induced gelification using sodium alginate and pectin. These microspheres were investigated for micromeritic properties, drug entrap...
EFFECT OF SUB MAXIMAL EXERCISE ON ENDOTHELIUM-DERIVED NITRIC OXIDE CONCENTRATIONS IN HEALTHY YOUNG SUBJECTS.
Objective: To determine any possible contribution of 10 minutes single session sub maximal exercise on Nitric oxide level in healthy young population. Design: A descriptive observational study on forty healthy volunteer...
FORMULATION AND EVALUATION OF FAST DISSOLVING TABLETS OF ROSUVASTATIN: RESEARCH ARTICLE
The objective of the present study was to formulate and evaluate fast dissolving tablets of Rosuvastatin (BCS Class II drug) to enhance solubility, improve bioavailability and patient compliance especially for the paedia...
POLYCYSTIC OVARY SYNDROME: PATHOGENESIS, TREATMENT AND SECONDARY ASSOCIATED DISEASES
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age. It is characterized by hyperandrogenism, polycystic ovaries, and chronic anovulation along with insulin resistance, hyperin...