Validation of Functional Assessment of Cancer Therapy with Nasopharyngeal Cancer Subscale (FACT-NP) for Quality of Life in Thai Patients
Journal Title: Journal of Health Science and Medical Research (JHSMR) - Year 2019, Vol 37, Issue 3
Abstract
Objective: To develop and validate the Thai version of the functional assessment of cancer therapy with nasopharyngeal cancer subscale (FACT-NP) with the abbreviated version of the World Health Organization Quality of Life-BREF instrument (WHOQOL-BREF). Material and Methods: A cross-sectional study was performed in the Radiology Department between January 2014 and October 2016. Inclusion criteria: nasopharyngeal carcinoma patients aged greater than 18 years. Exclusion criteria: no comprehension of the Thai language, had other cancers (except for skin cancer and diagnosed with impaired cognition and/or overt psychosis), major depression or delirium. After signing the consent form, participants were interviewed and self-completed FACT-NP and WHOQOL-BREF. The structure of the FACT-NP was determined with exploratory factors analysis. The internal reliability of identified domains was evaluated using Cronbach’s alpha. The correlation between domains of the modified FACT-NP and the domains of WHOQOL-BREF were examined with Spearman’s correlation. Known-group validity was determined by comparing patients with different sociodemographic and clinical characteristics using the T-test, Ranksum test and analysis of variance. A p-value of less than 0.05 was considered significant. Results: This study was terminated early due to a long accrual period. Of the 230 patients included in the study, only 220 completed both FACT-NP and WHOQOL-BREF. Exploratory factor analysis showed an accumulative variance of 0.56 with 4 factors. The internal reliability of modified FACT-NP was 0.92. There was moderate correlation between modified FACT-NP and WHOQOL-BREF. Both the modified FACT-NP and WHOQOL-BREF could identify differences between the groups. Conclusion: The Thai modified FACT-NP was found to be both valid and reliable for measuring the quality of life in Thai nasopharyngeal cancer patients.
Authors and Affiliations
Thanarpan Peerawong, Chanon Kongkamol, Zhiping Chen, Paytai Rordlamool, Duangjai Sangtawan, Rungarun Jiratrachu
Keywords
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- EP ID EP678078
- DOI http://dx.doi.org/10.31584/jhsmr.201958
- Views 177
- Downloads 0
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