VALIDATION OF THE FINNISH VERSION OF THE MONTREAL COGNITIVE ASSESSMENT TEST1
Journal Title: Acta Neuropsychologica - Year 2018, Vol 16, Issue 4
Abstract
The aim of this study was to determine the clinical utility of the Finnish version of the MoCA test for screening Alzheimer’s disease and MCI. The purpose was to examine the ability (sensitivity and specificity) of the MoCA to distinguish patients with AD and MCI from cognitively normal controls.<br/><br/>The study population consists of three participant groups: patients with AD (n=25), patients meeting the criteria for MCI (n=18), and cognitively normal controls (NC) (n=39). The AD group consists of subjects with very mild (CDR= 0.5, n=12), mild (CDR=1, n=12), and moderate (CDR=2, n=1) dementia, and they were given a diagnosis of dementia by using the revised NINCDS-ARDRA criteria. The normal control group (NC) consists of 39 cognitively normal volunteer participants.<br/><br/>The three study groups differed from each other in terms of sex, age, and level of education. The NCs were younger than the subjects with AD (t [37,374] = 3.265, p = 0.002) and MCI (t [30,800] = 4.306, p = < 0.001). The NCs were also better-educated than the patients with AD (t [54,975] = -3.419, p = 0.001) and MCI (t [40,782] = -3.008, p = 0.004). The sensitivity and specificity of the MoCA in detecting AD and MCI was done according to various cutoff points. With a cutoff score of 26, the MoCA had a sensitivity of 100% to detect subjects with AD and a sensitivity of 100% to detect subjects with MCI. The specificity was 79.5%. With a cutoff score of 24, which was the best threshold in the present study, the MoCA not only had a high sensitivity to detect subjects with AD (96%) and MCI (89%) but also delivered a high specificity (97%).<br/><br/>The MoCA has a high sensitivity and specificity to detect subjects with AD and MCI with a cutoff score of 24/30. The Finnish version of the MoCA is a feasible screening instrument for assessing cognitive decline. According to our study, the optimal cutoff score of the MoCA is 24/30.<br/><br/>
Authors and Affiliations
Taija Nortunen, Jukka Puustinen, Liisa Luostarinen, Heini Huhtala, Tuomo Hänninen
Keywords
Related Articles
- EP ID EP421763
- DOI 10.5604/01.3001.0012.7964
- Views 116
- Downloads 0
NEUROPSYCHOLOGICAL CONSEQUENCES OF CHILD ABUSE AND NEGLECT
The most dangerous kind of abuse is family violence. It occurs in the contextof a relationship of intimacy, kinship, trust and dependency, and mayhave physical, mental, or sexual forms. Family violence can take the form...
PERCEPTUAL LOAD MANIPULATION DOES NOT REVEAL SENSITIVITY ON THE N170 ERP COMPONENT OF MANIPULATED FACES AND BODIES
Background: It has been controversial in the face recognition literaturę whether face-sensitive N170 is affected by selective attention. Attention was manipulated according to Lavie’s perceptual load theory, examining th...
DEPRESSIVE SYMPTOMS AND WORKING MEMORY DYSFUNCTIONS IN PATIENTS WITH ISCHEMIC HEART DISEASE
Background: The problem of depression among patients with Ischemic Heart Disease (IHD) especially after myocardial infarction (MI) is well documented. Various levels of cognitive dysfunctions also constitute a frequent...
THE QUALITY OF LIFE OF A PATIENT WITH AN IATROGENIC BRAIN STROKE AFTER ANGIOSURGICAL TREATMENT FOLLOWING THE IMPLANT OF A STENTGRAFT INTO A DISSECTED THORACIC AORTA WITH A CONGENITAL ANATOMICAL ANOMALY OF BRANCHING OF THE RIGHT SUBCLAVIAN ARTERY (ARTERIA LUSORIA)
Background: The aim of this article was the evaluation of the quality of life of pa tient during long term follow up after the dissection of the descending thoracic aorta and angiosurgical related complications.Case stud...
CORRELATION OF THE THEORY OF MIND AND THE LEVEL OF COGNITIVE FUNCTIONING IN AUTISTIC CHILDREN
[b]Introduction.[/b] A deficit in theory of mind (ToM), i.e. an inability to conceive what others may be thinking or feeling, has often been posited as an essential feature of childhood autism. Our research goal was to s...