VALIDITY OF PATIENT REPORTED OUTCOME MEASUREMENT INFORMATION SYSTEM HEALTH ASSESSMENT QUESTIONNAIRE (PROMIS HAQ) FOR ASSESSING DISEASE ACTIVITY IN IRAQI PATIENTS WITH ACTIVE RHEUMATOID ARTHRITIS
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2014, Vol 6, Issue 8
Abstract
Objective: Rheumatoid arthritis (RA) is a chronic systemic autoimmune inflammatory disease that affects all ethnic groups throughout the world. Biochemical and clinical data are required to evaluate the disease activity and responsiveness to treatment. Disease activity score of 28 joints (DAS28) and simplified disease activity index (SDAI) are common tools that used to assess disease activity, whereas the Patient Reported Outcome Measurement Information System health assessment questionnaire (PROMIS HAQ) and HAQDI is a useful tool to assess the extent of the patient’s functional ability. This study aimed to evaluate the effectiveness of PROMIS HAQ score for monitoring disease activity and response to therapy in Iraqi patients with active rheumatoid arthritis.Methods: A cross-sectional study was conducted in Baghdad Teaching Hospital, Rheumatology outpatient Unit from September 2012 to April. A total of 140 patients (40 males and 100 females) with active RA were involved in this study Disease activity was measured by DAS28 and the SDAI whereas functional status of the patients was measured using PROMIS HAQ score.Results: There was a significant positive correlation of PROMIS HAQ score with clinical parameters like swelling joint count (SJC), tender joint count (TJC), visual analogue scale (VAS) and physician global assessment (EGA). Additionally PROMIS HAQ was significantly correlated with simplified disease activity index (SDAI). Furthermore it correlated with inflammatory marker CRP. Conclusion: PROMIS HAQ score is a valid and useful tool to monitor disease activity and response to treatment in Iraqi patients with highly active RA.Conclusion: PROMIS HAQ score is a valid and useful tool to monitor disease activity and response to treatment in Iraqi patients with highly active RA.Â
Authors and Affiliations
Samer Imad Mohammed
Keywords
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