Various Analytical Methods for Analysis of Sitagliptin – A Review
Journal Title: International Journal of Current Science Research and Review - Year 2024, Vol 7, Issue 08
Abstract
Sitagliptin is a dipeptidyl- peptidase inhibitor used to treat high blood sugar levels caused by type2 diabetes. Absorption of Sitagliptin is 87% orally bioavailable and taking it with or without food does not affect its pharmacokinetics. Sitagliptin reaches maximum plasma concentration in 2 hours. Now in this present analytical research world quality by design or design by expert technique is used to get improved method for method validation. This concise review work can guide an analyst to choose most appropriate method for a best analytical method development and validation. This assessment encompasses various analytical methods such as UV Spectrophotometry, High performance liquid chromatography [HPLC], Liquid chromatography – Mass spectrometry (LC-MS), High performance thin layer chromatography (HPTLC) and Ultra performance liquid chromatrography (UPLC) for the estimation of sitagliptin in single and/or in combination.
Authors and Affiliations
Tadikonda Rama Rao, Dasam Bhagyalakshmi,
Keywords
Related Articles
- EP ID EP743113
- DOI 10.47191/ijcsrr/V7-i8-80
- Views 40
- Downloads 0
The Correlation between Self-Confidence and Social Anxiety among Secondary and High School Students in Bangkok, Thailand
Social anxiety disorder (SAD) is a debilitating condition characterized by a marked and persistent fear of being humiliated or scrutinized by others. It is the third most common mental health disorder and has its origins...
Systematic Literature Review: The Influence Culture Organization and Motivation Work against Organizational Citizenship Behavior (OCB)
Overview literature systematic this aim for now influence culture organization, and motivation Work towards organizational citizenship behavior (OBC). Writing method review literature systematic. This is with sourced lib...
Balinese Lexicons Related to Segehan Offerings: An Ecolinguistics Study
Balinese Hindu Religion has various types of offerings from the simple ones to the most extravagant ones. Segehan is one of the simplest offerings conducted to maintain the harmony of nature and humans. The word segehan...
Intelligent Urban Systems and Industry 5.0: Creating Adaptive Ecosystems for Sustainable Energy and Resource Management
The rapid urbanization and growing complexity of cities demand innovative approaches to resource management and sustainability. This study introduces an adaptive ecosystem model for intelligent urban systems, integrating...
The Impact of Implicatures on the Interpretation of Indirect Speech Acts in “William Saroyan's the summer of The Beautiful White Horse”
This study explores “the impact of implicatures on the interpretation of indirect speech acts in William Saroyan’s The Summer of the Beautiful White Horse.” Using qualitative literary analysis, the study explores how im...