Viral bronchiolitis in young infants: new perspectives for management and treatment
Journal Title: Jornal de Pediatria - Year 2017, Vol 93, Issue 0
Abstract
Objective The aim of this review was to address advances in management and treatment of acute viral bronchiolitis in infants. Sources A systematic review search was made including all articles published in English between 2010 and 2017, and available in the electronic databases PubMed and Cochrane Central Register of Controlled Trials (CENTRAL) and specialized register of the Acute Respiratory Infections Group (Cochrane review group). The following MESH terms in English were included, using different Boolean operators for the search strategy: “bronchiolitis, viral,” “diagnosis,” “epidemiology,” “etiology,” “therapy,” “virology,” “prevention and control,” “respiratory syncytial virus, human.” Additional filters were used. Summary of findings Few effective interventions are recommended for the management of RSV bronchiolitis in young infants. The main goal is to ensure an adequate oxygen supplementation and fluid balance whenever deemed necessary. Hypertonic saline nebulization is helpful only for hospitalized infants. Numerous antiviral drugs and specific vaccines for RSV are under evaluation and foretell advances in disease management in the near future. Conclusion A number of promising new technologies are advancing in the field. Until new interventions became feasible, early detection and modification of preventable risk factors is essential to improve outcomes.
Authors and Affiliations
Mauricio Caballero
Keywords
Related Articles
- EP ID EP503468
- DOI 10.1016/j.jped.2017.07.003
- Views 47
- Downloads 0
Which children account for repeated admissions within 1 year in a Brazilian pediatric intensive care unit?
Objective While studies have focused on early readmissions or readmissions during the same hospitalization in a pediatric intensive care unit, little is known about the children with recurrent admissions. We sought to as...
Reviewing the use of corticosteroids in bronchopulmonary dysplasia
Objective Review the risks and benefits of postnatal corticosteroid use for the treatment of bronchopulmonary dysplasia, considering that there is not a more effective therapy. Data sources The literature review was car...
Preterm birth: temporal trends and socioeconomic inequalities
Socioeconomic inequalities in perinatal health have been consistently observed across many high- and low-middle income countries.1 Quantifying and monitoring socioeconomic inequalities in health is an important first ste...
Trp64Arg polymorphism of the ADRB3 gene associated with maximal fat oxidation and LDL-C levels in non-obese adolescents
Objective To analyze the association between the Trp64Arg polymorphism of the ADRB3 gene, maximal fat oxidation rates and the lipid profile levels in non-obese adolescents. Methods 72 schoolchildren, of both genders, ag...
Water and fluid intake in the prevention and treatment of functional constipation in children and adolescents: is there evidence?
Objective To study the evidence on the role of water and fluid intake in the prevention and treatment of functional intestinal constipation in children and adolescents. Source of data A search was carried out in the Med...