Viral co-infections among children with confirmed measles at hospitals in Hanoi, Vietnam, 2014
Journal Title: Asian Pacific Journal of Tropical Medicine - Year 2017, Vol 10, Issue 2
Abstract
Objective: To characterize viral co-infections among representative hospitalized measles cases during the 2014 Hanoi outbreak. Methods: Throat swabs were collected from 54 pediatric patients with confirmed measles, and molecular diagnostics performed for 10 additional viral respiratory pathogens (Influenza A/H1N1pdm09; A/H3N2 and influenza B; Parainfluenza 1, 2, 3; Respiratory Synctial Virus, RSV; human Metapneumovirus, hMPV; Adenovirus and Picornavirus). Results: Twenty-one cases (38.9%) showed evidence of infection with other respiratory viruses: 15 samples contained measles plus one additional virus, and 6 samples contained measles plus 2 additional viruses. Adenovirus was detected as a predominant cause of coinfections (13 cases; 24.1%), followed by RSV (6 cases; 11.1%), A/H1N1pdm09 (3 cases; 5.6%), PIV3 (3 cases; 3.7%), Rhinovirus (3 cases; 3.7%) and hMPV (1 case; 1.96%). Conclusions: Viral co-infections identified from pediatric measles cases may have contributed to increased disease severity and high rate of fatal outcomes. Optimal treatment of measles cases may require control of multiple viral respiratory pathogens.
Authors and Affiliations
Hang Khanh Nguyen, Mai Quynh Le
Keywords
Related Articles
- EP ID EP278467
- DOI 10.1016/j.apjtm.2017.01.015
- Views 78
- Downloads 0
Echinococcosis in Pakistan: One Belt & One Road Initiative
Cystic echinococcosis (CE) is zoonotic neglected tropical parasitic disease. It is endemic in the some Asian countries like China, Turkey, Iran and India. In Pakistan it is neglected and limited studies have been conduct...
Zika virus is arriving at the American continent
Zika virus (ZIKV) is the last arbovirosis to arrive to the American continent, following dengue virus (DENV) in 1990, West Nile virus (WNV) in 1999 and chikungunya (CHIK) at 2013. At this time, it represents a pandemic a...
Identification and analysis of a processed cytochrome P450 pseudogene of the disease vector Aedes aegypti
Objective: To clone cytochrome P450 from Aedes aegypti (Ae. aegypti) and determine the characteristics using bioinformatics tools. Methods: Cytochrome P450 of Ae. aegypti was amplified using polymerase chain reaction, cl...
Antitumor effect of thymoquinone combined with resveratrol on mice transplanted with breast cancer
Objective: To test the anticancer potential activity of the combination of thymoquinone (TQ) and resveratrol (RES) against breast cancer in mice. Methods: The antiproliferative activity of TQ, RES and their combination w...
Chemical composition, antioxidant, and antibacterial activity of essential oils from Etlingera sayapensis A.D. Poulsen & Ibrahim
Objective: To report the chemical composition and bioactivity (including antioxidant and antimicrobial activity) of essential oils from the rhizomes, stems, and leaves of Etlingera sayapensis (E. sayapensis) A.D. Poulsen...