Vitamin C’s Variant Effects on Covid-19 Patients: A Breif Review
Journal Title: International Journal of Health & Medical Research - Year 2022, Vol 1, Issue 01
Abstract
The target is to evaluate ascorbic acid effect on prevention or treatment of the most recent viral infection, SARS-CoV-2. Covid-19 is a Systemic disease that can cause a sharp increase in cytokines, resulting in pulmonary capillary endothelial cell activation. Increasing neutrophil infiltration and oxidative stress. Coronavirus activates macrophages to release molecules such as NO. Vitamin C enhance chemotaxism, migration and decreases ROS release. It also reduces the secretion of cytokines, especially 6-IL and TNF-α. Vitamin C can help increase the rate of recovery in hospitalization by 70% and quantitative analysis indicated that it may reduce patients' symptoms by 30%. High dose Ascorbic acid infusion causes positive interference in sodium, glucose and creatinine also negative interference in lipase, Triglycerides, direct bilirubin and LDL / HDL cholesterol. Co-treatment of vitamin C with Melatonin, Vitamin D and Zinc can have a synergic effect on treatment. Although; in a study high doses of zinc gluconate and ascorbic acid, had no significant effect on reducing the course of symptoms.
Authors and Affiliations
Maryam sanei, Parisa motififard, Yalda Askari sadat mahalleh, Saba zaeri, Setayesh mostafavi, Asal Mohseni, Mahsa Mazaheri tirani, Sasan heidariesfahani, Hossein Esmaeili
Keywords
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