Vitamin D Deficiency and its Relation to Lipid Profile

Abstract

The article explained the relation between deficiency in vitamin D and increase parameters of lipid profile in the serum. Therefore, correction of vitamin D deficiency will lower the lipid profile parameters and so protect the heart from diseases.Vitamin D deficiency and its relation to lipid profileBackground:Vitamin D deficiency is considered as a major public health problem all over the world. Vitamin D acts as a hormone with multi-functions. The main source of vitamin D is solar UV radiation, which converts 7-dehydrocholesterol to pro-vitamin D which is modified to vitamin D given normal skin temperature. Vitamin D deficiency is a common disorder presents in all ages and in both genders.Vitamin D plays an important role in modulating the immune response to infections and reduction inflammatory response. Vitamin D deficiency has a genetic predisposition. There is a correlation between low 25-hydroxyvitamin D levels and dyslipidemia, so correction of vitamin D deficiency is important for treating disturbance in lipid profile. Repletion of 25-hydroxy vitamin Dlevels raised serum calcium level and decrease parathyroid hormone levels.Materials:The study was carried out in a clinical Lab Al-Safowa in Cairo , Egypt on blood samples taken from 39 female patients, in the period from October 2019 to May 2020. Patients aged between (25-45) years old, all suffering from vitamin D deficiency indicated by unclear bony pain . The blood samples were estimated for lipid profile by fasting serum samples using colorimetric method and vitamin D estimation by ELIZA. The results were analyzed using SPSS (T-Test).Results:There were significant correlation between vitamin D deficiency and hypercholesterolemia and increase LDL levels(P<0.05) but insignificant correlation between vitamin D deficiency and HDL and TG ( significant P value > 0.05). Conclusions:Vitamin D deficiency is correlated with increase inLDL, cholesterol. Recommendation:It is important to correct vitamin D deficiency to treat hyperlipidemia and so protection from cardiovascular diseases.Aim of thework: to explain the relation between deficiency in serum level of vitamin D and disturbance in lipid profile.

Authors and Affiliations

Marwa F. Elmahdy, Moaz A. Mousa, Souhail A. Mounir

Keywords

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  • EP ID EP739777
  • DOI 10.47191/ijmscrs/v3-i2-03
  • Views 4
  • Downloads 0

How To Cite

Marwa F. Elmahdy, Moaz A. Mousa, Souhail A. Mounir (2023). Vitamin D Deficiency and its Relation to Lipid Profile. International Journal Of Medical Science And Clinical Research Studies, 3(2), -. https://europub.co.uk/articles/-A-739777