VITAMIN D LEVELS IN DEPRESSIVE DISORDER
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2019, Vol 6, Issue 11
Abstract
BACKGROUND There is a dearth of studies evaluating the role of vitamin D in depression in Kerala, which has a high prevalence rate of depressive disorder and suicide. In this study, we aimed to compare the levels of vitamin D of 50 depressed patients with that of 50 age matched controls. MATERIALS AND METHODS This is a case control study, conducted in a tertiary care teaching hospital in Kochi, Kerala between October 2012 and October 2014 (2 years). The vitamin D levels of 50 (cases) patients diagnosed to have depressive disorder as per the International Classification of Disease, 10th revision; Diagnostic Criteria for Research (ICD-10-DCR) were compared to 50 age matched controls. The vitamin D levels were estimated from the venous blood samples by using Abbot Architect i. RESULTS In this study, 58% (29) of the cases and 26% (13) of the controls had Vitamin D deficiency. The difference was statistically significant (p-value <0.001). CONCLUSION In this study, the serum vitamin D levels are significantly lower in cases than in the controls. Vitamin D deficiency is common and often unrecognized and yet may be an important contributor to depressive disorder. Further case control studies with larger random samples are needed to establish the association of vitamin D deficiency with depression.
Authors and Affiliations
Angel Abraham, Sajitha Krishnan, Kuzhikandathil Narayanan Subhakumari, Geomy George Chakkalakkudy
Keywords
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- EP ID EP615544
- DOI 10.18410/jebmh/2019/181
- Views 78
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