VITAMIN D LEVELS IN DEPRESSIVE DISORDER
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2019, Vol 6, Issue 11
Abstract
BACKGROUND There is a dearth of studies evaluating the role of vitamin D in depression in Kerala, which has a high prevalence rate of depressive disorder and suicide. In this study, we aimed to compare the levels of vitamin D of 50 depressed patients with that of 50 age matched controls. MATERIALS AND METHODS This is a case control study, conducted in a tertiary care teaching hospital in Kochi, Kerala between October 2012 and October 2014 (2 years). The vitamin D levels of 50 (cases) patients diagnosed to have depressive disorder as per the International Classification of Disease, 10th revision; Diagnostic Criteria for Research (ICD-10-DCR) were compared to 50 age matched controls. The vitamin D levels were estimated from the venous blood samples by using Abbot Architect i. RESULTS In this study, 58% (29) of the cases and 26% (13) of the controls had Vitamin D deficiency. The difference was statistically significant (p-value <0.001). CONCLUSION In this study, the serum vitamin D levels are significantly lower in cases than in the controls. Vitamin D deficiency is common and often unrecognized and yet may be an important contributor to depressive disorder. Further case control studies with larger random samples are needed to establish the association of vitamin D deficiency with depression.
Authors and Affiliations
Angel Abraham, Sajitha Krishnan, Kuzhikandathil Narayanan Subhakumari, Geomy George Chakkalakkudy
Keywords
Related Articles
- EP ID EP615544
- DOI 10.18410/jebmh/2019/181
- Views 64
- Downloads 0
GOLDENHAR SYNDROME- ANAESTHETIC MANAGEMENT
PRESENTATION OF THE CASE A 6-month-old male child presented to Ophthalmology Outpatient Department of our hospital with decreased vision and painless swelling near left eye since birth. On ophthalmic examination, the chi...
ESTIMATION OF HEIGHT FROM THE LONG BONES OF LOWER LIMB AND FOOT DIMENSIONS IN SOUTH INDIAN POPULATION
Establishment of an identity is very much important in both civil and criminal cases. Stature is one of the criteria of personal identification. Many studies have shown that limbs exhibit consistent ratios relatives to t...
DIABETIC FOOT: PREVALENCE, KNOWLEDGE, AND FOOT SELF-CARE PRACTICES AMONG DIABETIC PATIENTS IN A TERTIARY CARE HOSPITAL IN PONDICHERRY
BACKGROUND Diabetes is a global epidemic with devastating human, social and economic consequences associated with various short and long-term complications, many of which, have the potential to reduce the quality of life...
TUBERCULAR GRANULOMA OF CESAREAN SECTION WOUND: ‘DIAGNOSED IN IMMEDIATE POST-OPERATIVE PERIOD OF CASESAREEN SECTION BY SKIN BIOPSY’
20 yr old primigravida with postdated pregnancy taken for cesarean section with an indication of failure to progress. Uneventful surgery post operatively developed skin sloughing, gangrene and necrosis. Biopsy yielded th...
STUDY OF COMMUNICATIONS BETWEEN MUSCULOCUTANEOUS NERVE AND MEDIAN NERVE IN ADULT CADAVERS
BACKGROUND Variations of the musculocutaneous nerve and the median nerve, like the communications between the two, may prove valuable in the traumatology of the shoulder joint and upper arm region. These variations are i...