Vitamin D status and bone turnover marker levels in Greek women with fragility hip fracture
Journal Title: International Journal of Orthopaedics Sciences - Year 2017, Vol 3, Issue 1
Abstract
There is little data regarding Vitamin D deficiency in Greece. Also conflicting are the data regarding the bone turnover during the acute hip fracture interval and the situation is even more complex considering the recently developed bone turnover markers (BTMs). The aim of this study was to evaluate the parameters of bone mineral homeostasis of women with fragility hip fracture using the recently developed BTMs of carboxy-terminal collagen crosslinks (CTx) and the procollagen type 1 amino-terminal propeptide (PINP) and to determinate vitamin D (25-OHD) levels of elderly Greek women with acute hip fracture. 38 self-sufficient, community-living Greek women with acute hip fracture were included. A similar number of age- and sex-matched controls with no clinically evident fractures were included in the study meeting the same inclusion and exclusion criteria. To exclude the effect of trauma blood samples were drawn within 24 hours from the fracture. Hip fracture group had significantly lower serum 25-OHD levels and significantly higher intact parathormone (PTH) levels compared to the control group but no correlation between PTH and 25-OHD was found in both groups. CTx was significantly correlated with PINP in the total group and in both groups separately but there was no statistical difference of their levels between the two groups. There was high prevalence of severe Vitamin D deficiency within the postmenopausal Greek women with acute hip fracture and the fracture did not influence the above mentioned BTMs. The processes of bone resorption and bone production are in balance during the first 24 hours after the fracture.
Authors and Affiliations
Efstathios Drampalos, Lazaros Oikonomidis, Jeremy Oakley, Ioannis Michos
Keywords
Related Articles
- EP ID EP500474
- DOI 10.22271/ortho.2017.v3.i1i.81
- Views 116
- Downloads 0
Evaluation of the functional outcome in open tibial fractures managed with an Ilizarov fixator as a primary and definitive treatment modality
Introduction: Open fractures are rapidly compounding problem for trauma surgeons. Open fractures of leg, which are perhaps the most common among open fracture, were taken as prototype in which extra articular fracture of...
Functional outcome of subtrochanteric fracture fixed with long proximal femoral nail
Background: Subtrochanteric fractures are fractures that occur in a zone extending from the lesser trochanter to 5cm distal to the lesser trochanter, however extension into the intertrochanteric region is common. These f...
Results of single row versus double row arthroscopic repair in massive rotator cuff tear
Introduction: Rotator cuff disease is a painful condition with a multifactorial aetiology in which severe or chronic impingement of the rotator cuff tendons on the under- surface of the coracoacromial arch is often a sig...
Avascular necrosis of the femoral head due to sickle-cell disease in tribal population around Vishakhapatnam district, treated with core de-compression and non - vascularised fibular graft
Sickle-cell disease (SCD) is the most common cause of avascular necrosis (AVN) of the hip in childhood. It results in significant physical impairment and chronic pain, and ohen progresses to require hip replacement. Cons...
Short term outcome analysis of proximal tibia fractures treated with minimally invasive plate osteosynthesis
Introduction: Proximal tibial fractures caused by high-energy mechanisms are associated with neurovascular injuries, compartment syndrome, deep vein thrombosis, contusion, crush injury to the soft tissues and open wounds...