Vitamin D status in patients with hypothyroidism
Journal Title: Medpulse International Journal of Medicine - Year 2017, Vol 4, Issue 2
Abstract
Background: Vitamin D deficiency and hypothyroidism are common problems in India. Vitamin D not only has action on calcium metabolism, but its deficiency is considered as cause for autoimmune diseases. Currently, only animal trials are available, cause and effect relationship between vitamin D deficiency and autoimmune diseases is yet to be proved in human beings. Hypothyroidism is also known to have effects on calcium homeostasis. Our aim was to study vitamin D status in hypothyroid patients and compare it with normal controls. Subjects and Methods: We studied 50 patients with hypothyroidism and 50 normal controls who visited our outpatient department. Vitamin D levels and thyroid profile were sent in all 100 patients. Vitamin D deficiency was designated at <20ng/ml. Results: Vitamin D deficiency was found in 73% of patients with hypothyroidism. Even among hypothyroid patients, people with TSH under normal limits vitamin D deficiency prevalence (45% in hypothyroid patients) were comparable to that of normal controls (44% in controls). T test was applied between uncontrolled hypothyroid group and normal control group and p value was 0.0023, t= 2.9. There was no statistical significance difference between males and females t=1.3, p=0.08. There was negative correlation between TSH levels and vitamin D levels in patients with hypothyroidism suggesting the uncontrolled the hypothyroidism the lower would be the vitamin D levels. Conclusion: Vitamin D levels must be checked in all hypothyroid patients, specifically in people with age 50-59 years, uncontrolled hypothyroidism as both uncontrolled hypothyroidism and vitamin D deficiency may present with similar nonspecific complaints.
Authors and Affiliations
Hari kishan jayanthi, Sai Krishna Tulasi, Jagannadha Phaneendra D S
Keywords
Related Articles
- EP ID EP478737
- DOI 10.26611/10214233
- Views 67
- Downloads 0
A Study of Hormonal assay among adolescent patients with acne between 15 to 20 at tertiary health care centre
Background: Acne vulgaris is a common disorder of the pilosebaceous unit. It means prevalence in adolescence is estimated to be 70-87%. Aims and Objectives: To Study Hormonal assay among adolescent patients with acne bet...
A clinical profile of the patients with malaria at tertiary health care center
Background: Malaria remains, as it has been for centuries, one of the most serious parasitic diseases worldwide, affecting 300–500 million people and causing over 1 million deaths annually. Aims and Objectives: To study...
Study of diffusion capacity of lung for carbon monoxide (DLCO) in chronic obstructive pulmonary disease
Background: The most useful test of the gas exchange capacity of the lung that correlates with the total functioning surface area of alveolar capillary interface is the DLCO. Aims and Objectives: To Study Diffusing Capa...
A study of clinico- laboratory profile of the patients with type II diabetes at rural tertiary health care center
Background: The relationship between alteration of serum lipids and vascular complications is more significant in diabetics than in non diabetics amongst the general population. Lipid abnormalities will lead to microvasc...
A cross sectional study on the assessment of cardiac autonomic dysfunctions among patients with type 2 diabetes mellitus
Background: Neuropathy is a common complication of diabetes mellitus. It may affect both peripheral and autonomic nervous system. The objective of the present study was to investigate the prevalence of cardiac autonomic...