VITAMIN D3 LEVEL IN TYPE 2 DIABETES MELLITUS AND ITS CORRELATION WITH HbA1c LEVEL- A CROSS-SECTIONAL STUDY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 32
Abstract
BACKGROUND The role of vitamin D in type 2 diabetes is suggested by a seasonal variation in glycaemic control. It was reported in patients with type 2 diabetes being worse in winter, which might be due to hypovitaminosis D as a result of reduced exposure to sunlight. Aims and Objectives- (I) To estimate the plasma vitamin D3 level in type 2 diabetes mellitus. (II) To find out association between vitamin D3 and HbA1c level. (III) Correlation between serum vitamin D3 level and diabetic cardiovascular complications. MATERIALS AND METHODS A cross-sectional study was conducted among 100 type 2 diabetes patients who were selected from medicine ward and diabetes clinic. The descriptive statistics like percentages, mean and median were calculated. The inferential statistics like Chi-square statistics and Spearman’s correlation were performed for analysis of data. RESULTS HbA1c was increased in majority of patients (71.0%). Majority of the respondents were having low vitamin D levels. There was gross scattering of the dots indicating that poor correlation between HbA1c and Vitamin D levels. The Spearman’s Rho was found to be only 0.092 (poor correlation) and this finding was not significant (p= 0.361). There was poor correlation between HbA1c and Vitamin D3 levels and Vitamin D3 level was not correlated with age and hypertension. CONCLUSION The 25-(OH) D3 concentrations were low in 90% of the diabetic patients. There was an inverse association between the serum concentration of 25-(OH) D3 and type 2 diabetes, thereby suggesting a protective role of vitamin D against the development of the disease.
Authors and Affiliations
Gautam Debbarma, Santosh Reang, Taranga Reang
ENDOSCOPIC FAT GRAFTING OF SMALL AND RESIDUAL TYMPANIC MEMBRANE PERFORATIONS- A CLINICAL STUDY
BACKGROUND Fat patch grafting is a simple effective alternative to conventional tympanoplasty in dealing with carefully selected small central tympanic membrane perforations. Despite its numerous advantages and relative...
EVALUATION OF MENORRHAGIA AND ITS CORRELATION WITH HYSTEROSCOPY AND HISTOPATHOLOGY OF ENDOMETRIUM
BACKGROUND Menorrhagia is one of the most frequent complaint among women to see a gynaecologist. Clinically menorrhagia is total blood loss exceeding 80 mL/cycle and/or menses lasting later than 7 days.[1] About 66% of a...
QUALITY OF LIFE, SEXUAL SATISFACTION AND PSYCHIATRIC CO-MORBIDITY IN WOMEN POSTED FOR HYSTERECTOMY
BACKGROUND Uterus holds a deeply symbolic meaning to women. Its removal can have a significant effect on one’s quality of life, sexual functioning and psychological well-being. Aims and Objectives- To evaluate the qualit...
A COMPARISON BETWEEN INTRAVENOUS PARACETAMOL PLUS INTRAVENOUS FENTANYL AND INTRAVENOUS FENTANYL PLUS INTRAVENOUS KETOROLAC FOR POSTOPERATIVE ANALGESIA DURING LAPAROSCOPIC CHOLECYSTECTOMY
BACKGROUND Studies have suggested a large inter-individual variation in postoperative pain after laparoscopic cholecystectomy, emphasising the need for improved analgesic treatment and valid predictors. Our study compare...
SODIUM VALPROATE VERSUS FOSPHENYTOIN FOR STATUS EPILEPTICUS IN CHILDREN- A RANDOMIZED CONTROL TRIAL
BACKGROUND Status epilepticus (SE) is a life-threatening neurological emergency in children associated with high morbidity and mortality. Phenytoin/fosphenytoin is the currently recommended first choice second line treat...