Vitamin-mineral premix and treatment of diffusive nontoxic goiter

Abstract

Background. The content of microelements and vitamins was studied in adolescents with diffuse nontoxic goiter (DNG). The purpose of the study is to substantiate the use of vitamin-mineral premixes in the treatment of adolescents with DNG. Materials and methods. In 109 girls and 97 boys aged 9–17 years with DNG, the content of vitamins (A, E, B1 and B2), essential (Se, Zn) and toxic (Pb, Cd, Co) trace elements was evaluated taking into account the functional state of the thyroid system and the goiter course. Results. The degree of vitamin and microelement imbalance influences the formation and course of DNG. It was found that the unfavorable course of DNG occurs against the background of a significant decrease in the content of vitamin A, Se and Zn and excessive accumulation of Pb and Cd. The nature of the relationship between the functional state of the thyroid system, the content of vitamins and microelements were studied in patients with DNG. It is proved that treatment and secondary prevention of DNG involves not only the use of potassium iodide preparations, but also correction of vitamin-mineral imbalance with additional prescription of Se, Zn, group A, E and B vitamins. Conclusions. Imbalance of vitamins and microelements is an additional factor in the formation of DNG in conditions of mild iodine deficiency. The unfavorable course of DNG occurs against the background of a decrease in the level of vitamin A, essential trace elements (Se and Zn) and excessive accumulation of toxic trace elements (Pb and Cd). Correction of vitamin-mineral imbalance is a necessary component of the treatment for DNG and prevention of its unfavorable course. In case of a decrease in the Se level, it is advisable to use the antioxidant complex OxyLyc, and in case of zinc deficiency, Zinkit is prescribed additionally.

Authors and Affiliations

S. I. Turchina

Keywords

Related Articles

Peculiarities of Ischemic Heart Disease Course and Treatment in Patients with Glucose Metabolism Impairment and Diabetes Mellitus

Combination of ischemic heart disease and diabetes mellitus is characterized by certain features of clinical picture and insufficient effectiveness of treatment of ischemic heart disease. With the aim of investigation of...

Complex Clinical-Laboratory and Cytological Study of Cervical and Vaginal Discharge in Women with Endocrinopathies

Cytological examination is one of basic methods for morphological analysis of biological material. It consists in the evaluation of characteristics of the morphological structure of cellular elements in cytological speci...

The Dynamics of Iodine Deficiency Disorders in the Republic of Karakalpakstan Based on the Epidemiological Studies of 1998, 2004 and 2014

The article summarizes the results of monitoring for iodine deficiency disorders in Karakalpakstan from 1998 to 2014. In accordance with the WHO recommendations, there were assessed the following indicators: the prevalen...

The relation of the dynamics of anthropometric data in obese women of childbearing age with treatment type

The aim was to study efficiency of pathogenetic therapy and dynamics of anthropometric indexes in obese women of childbearing age having different endocrine patho­logy before and 6 months later after treatment. Materials...

Associations between Mycoplasma and Components of Immune Response in Women with Autoimmune Thyroiditis

There was investigated immunoglobulin G (IgG) to the mycoplasma (Mp) in the blood serum of women with autoimmune thyroiditis (AIT) of reproductive age and in postmenopausal periods. A control group consisted of women of...

Download PDF file
  • EP ID EP275707
  • DOI 10.22141/2224-0721.14.1.2018.127094
  • Views 37
  • Downloads 0

How To Cite

S. I. Turchina (2018). Vitamin-mineral premix and treatment of diffusive nontoxic goiter. Міжнародний ендокринологічний журнал, 14(1), 59-66. https://europub.co.uk/articles/-A-275707