Vogt-Koyanagi-Harada-Syndrome Concurrent with Morbus Darier
Journal Title: Journal of Rheumatic Diseases and Treatment - Year 2016, Vol 2, Issue 2
Abstract
Vogt-Koyanagi-Harada-syndrome (VKH) is a multisystemic, T-cell mediated autoimmune disorder which is characterized by bilateral granulomatous panuveitis with extraocular manifestations in the central nervous and auditory system as well as in the integumentary field. Neurological and auditory manifestations include aseptic meningitis, meningism, tinnitus and cerebrospinal fluid pleocytosis. Integumentary findings can include alopecia, poliosis and vitiligo. The etiology of this disease is thought to be an immune reaction against melanocytes.
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