Vulvar Lesion Mimicking Vitiligo Revealing a Squamous Cell Carcinoma
Journal Title: Journal of Dermatology Research - Year 2023, Vol 4, Issue 1
Abstract
Melanocytes respond to trauma or cutaneous inflammation by producing varying amounts of melanin, which manifests as either hyperpigmentation or hypopigmentation. Post inflammatory Hypopigmentation (PIH) is an acquired partial or total loss of skin pigmentation that occurs after cutaneous inflammation or injury [1]. Mechanisms and pathogenesis of PIH remain unclear. It is difficult to understand how individuals respond to inflammation differently. Skin discoloration is the primary clinical indication of pigment incontinence [2]. Vitiligo, another disease that presents similarly, is often confused with PIH. Significant contrast in wood light and dermoscopy can lead to a positive diagnosis of vitiligo. The most common malignant neoplasm affecting the vulva is Vulvar Squamous Cell Carcinoma (VSCC). It accounts for approximately 90% of all cases of vulvar cancer. The majority of female vulvar squamous cell cancer cases occur after menopause [3]. The causes of VSCC are multifactorial, with a number of risk factors identified, including infection with Human Papillomavirus (HPV), chronic inflammation, and immunodeficiency [4].
Authors and Affiliations
Imane Kacimi Alaoui, Zakia Douhi, Siham Boularbah, Meryem Soughi, Sara Elloudi, Hanane Baybay, Fatima-Zahra Mernissi
Keywords
Related Articles
- EP ID EP715201
- DOI https://doi.org/10.46889/JDR.2023.4108
- Views 62
- Downloads 0
Dermatological Manifestations during SARS-CoV-2 (COVID-19) on Phototype VI in Thiès/Senegal (West Africa)
Introduction: Dermatological manifestations are extremely polymorphic, increasingly reported on Caucasian skin. Few studies have been conducted on phototype VI which justifies our work whose objectives were to study the...
Isolated Eyebrows and Eyelashes Trichoteiromania Mimicking Alopecia Areata
A 23-year-old woman, with no pathological history, was treated for alleged alopecia areata of her eyebrows and eyelashes by her usual dermatologist before being referred to our institution after treatment failure. The...
Clinico-Mycological Profile of Dermatophytic Skin Infection: Cross Section Study
Background: Dermatophytoses, commonly known as “ringworm”, are superficial fungal infections that affect the skin, hair, and nails. Objective: To evaluate the clinical features of dermatophyte infection and identify t...
The Nails in Fine Arts
The observation of the nails represented in art masterpieces encourages to catch details which allow us to suspect skin disorders of the past, still commonly encountered in our daily clinical activity. Nails are cutaneou...
Clinicopathological Correlation in Dermatopathology
Introduction and aim: Getting an accurate diagnosis in dermatopathology requires a combination of clinical and pathological information. Our aim was to assess the importance of the correlation between clinical and histop...