Warfarin Therapy Monitoring of Cardiac Care Patients in Hospital in Bandung
Journal Title: Indonesian Journal of Clinical Pharmacy - Year 2012, Vol 1, Issue 3
Abstract
The aims of this study were to identify the rational warfarin monitoring therapy to guarantee the right dose, therapy security, and whether the dose of warfarin therapy has completed the rational criteria or not. Degree of antikoagulasi for each patient is measured with protombin time as International Normalized Ratio (INR). The methods consist of warfarin monitoring therapy towards 80 patients at the heart service through the PT-INR constant, medical data, such as age, gender, weight, height, type of the disease, dose usage and another medicine which is used together, and statistical test of the average of INR. The monitoring result shows that patient’s INR average is 1,38 ±0,42, the result of ANAVA (α=0,05) shows that there’s no impact of dose towards INR (p=0,13) but there’s an INR average impact based on gender (p=0,051), age (p=0,397) and dose variation (p=0,057). The results shown that warfarin dose which used is not bleeding risk.
Authors and Affiliations
Norisca A. Putri, Keri Lestari, Ajeng Diantini, Taofik Rusdiana
Keywords
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