We can Diagnose it if we Consider it. Diagnostic Pitfall for Placenta: Placental Mesenchymal Dysplasia
Journal Title: Turkish Journal of Pathology - Year 2018, Vol 34, Issue 1
Abstract
Placental mesenchymal dysplasia is an increasingly recognizable abnormality. Early cases have been confused with partial hydatidiform mole. Placental mesenchymal dysplasia is probably under-diagnosed because of being an unfamiliar clinical entity and also mistaken for gestational trophoblastic disease due to the similar sonographic findings of two entities. In this report, we describe the clinical, gross, and histopathological findings of placental mesenchymal dysplasia in two cases. The 33-week-preterm baby of a 26-year-old woman with cardiovascular disease and 342 gram placenta and the 19-week fetus with trisomy 21 of a 40 year-old woman were terminated. Macroscopically thick-walled vessels and microscopically hydropic villous with peripherally localized thick-walled vessels without trophoblastic cell proliferation were observed in both cases. These two cases represent a rare placental anomaly that is benign but it is challenging to distinguish placental mesenchymal dysplasia from an incomplete mole. Placental mesenchymal dysplasia should be included in the differential diagnosis of sonographic findings that show a normal appearing fetus and a placenta with cystic lesions. Placental mesenchymal dysplasia is associated with pregnancy-related hypertension. In conclusion, the most important point is “you can diagnose it if you consider it”.
Authors and Affiliations
Havva Serap TORU, Esra ÇOBANKENT AYTEKİN, Cem Yaşar SANHAL, Sezin Yakut, Zafer ÇETİN, İbrahim İnanç MENDİLCİOĞLU, Hadice Elif PEŞTERELİ
Keywords
Related Articles
- EP ID EP254787
- DOI 10.5146/tjpath.2015.01301
- Views 87
- Downloads 0
Pediatric Intracranial Ependymal Tumors: Clinicopathologic Evaluation of 28 Cases
Objective: In the present study we aimed to assess the prognostic value of age, tumor localization, extent of surgery, histological grade, p53 protein and Ki67 proliferation index in pediatric cases diagnosed as ependymo...
A Unique Immunofluorescence Protocol to Detect Protein Expression in Vascular Tissues: Tacking a Long Standing Pathological Hitch
Objective: Autofluorescence induced interference is one of the major drawbacks in immunofluorescence analysis of formalin-fixed paraffin-embedded tissues, as it decreases the signal-to-noise ratio of specific labeling. A...
Malignant Melanoma Presenting as a Mediastinal Malignant Melanoma Presenting as a Mediastinal Unknown Primary Origin?
The most common site of primary malignant melanoma is the skin, however, virtually any organ system may be involved. Metastatic melanoma of unknown primary origin accounts for approximately 2-6% of all melanoma cases. Th...
Angiocentric Glioma: The Infiltrative Glioma with Ependymal Differentiation
Angiocentric glioma is an epileptogenic, infiltrative, low grade glial tumor, with ependymal and astrocytic differentiation, most commonly seen in young adults and the pediatric age group. Herein we report a case of 21-y...
Congenital Complete Tracheal Ring in a Neonate: A Case Report
Abnormalities of the upper airway tract lead to congenital high airway obstruction and may complicate neonatal airway management in the delivery room. Congenital complete tracheal rings are a rare and unusual tracheal an...