What Should Be the Prostate Specific Antigen Threshold for Prostate Biopsy?
Journal Title: HASEKİ TIP BÜLTENİ - Year 2017, Vol 55, Issue 2
Abstract
Aim:There is still uncertainty today regarding the prostate specific antigen (PSA) threshold for prostate biopsy. From this point of view, we aimed to investigate the PSA threshold for prostate biopsy in this study. Methods: We retrospectively evaluated medical records of 375 patients, who underwent 12-16-core transrectal ultrasound-guided prostate biopsy between September 2012 and November 2015. The patients were divided into three groups according to the PSA values: group 1: 2.5-4ng/mL, group 2: 4.1-10 ng/mL and group 3: >10 ng/ mL. Age, prostate volume, prostate cancer detection rate, Gleason score, the average core length and the core length obtained per cc of prostate volume were compared between the groups. Results: The mean age of the patients was 64.39±7.62 years and the mean cancer detection rate was 26.7%, namely 11.5% (3/26), 17.4% (43/247) and 52.9% (54/102) in the groups 1, 2 and 3, respectively. Prostate cancer was not detected in any patient with a PSA value of <3.6 ng/mL (n=13). Conclusion: Since prostate cancer was not detected in any patient with a PSA value of <3.6 ng/mL in our study, we suggest higher PSA threshold values in order to reduce unnecessary prostate biopsy procedures.
Authors and Affiliations
Hasan Deliktaş, Hayrettin Şahin
Keywords
Related Articles
- EP ID EP228161
- DOI 10.4274/haseki.3212
- Views 110
- Downloads 0
Effect of Intraoperative Neuromonitoring on Voice Quality in Total Thyroidectomy
Aim: Thyroid gland surgery has a risk of serious complications. Advancements in technology have led to improvements in complications but significant challenges to preserving voice and airway function still remain. The pu...
Evaluation of Electroencephalography Findings in Isolated Hypocalcemia Patients
Aim: In our study, we aimed to analyze electroencephalography (EEG) findings in patients with hypocalcemia and to investigate possible relationship between calcium (Ca) level and EEG abnormalities and whether there was a...
Effect of Baseline Datas on the Survival of Intensive Care Unit Patients
Aim: We investigated demographic features and systemic diseases which affect mortality and the importance of the biochemical analyzes on admission in patients admitted to intensive care unit (ICU). Methods: We included 1...
Emergency Department Management Following the Sultanahmet Square Suicide Bombing in İstanbul: One Hospital’s Experience
.
The Acute Effect of Erythropoietin on Mean Platelet Volume Levels during Hypoxia Reoxygenation Injury in Rats
Aim: This biomedical study tested the effect of erythropoietin (Epo) in rat model, especially in a hypoxia-reoxygenation one. The trend of this factor was evaluated hematologically using serum mean platelets volume (MPV)...