White sponge nevus- A rare entity
Journal Title: IP Journal of Diagnostic Pathology and Oncology - Year 2017, Vol 2, Issue 1
Abstract
White sponge nevus (WSN) is an autosomaldominantly inherited form of mucosal leukokeratosis. It was first described by Hyde in 1909 and named by Cannon in 1935. Hence, it is also called Cannon's disease, hereditary leukokeratosis of mucosa, or white sponge nevus of Cannon. It is caused by a mutations in genes coding for keratin, which results in defective keratinisation. It is characterized by benign, painless, thick, white and spongy plaques of the oral mucosa. There is no gender predilection. Other extra oral sites include nasal, oesophageal, laryngeal, vaginal and anal mucosa.(1) The histopathologic features of WSN include epithelial thickening, hyperparakeratosis, and vacuolization of the keratinocytes in the suprabasal layers.(2) It is asymptomatic and therefore no treatment is required. Here is a case report of white sponge nevus in a 25 year old male affecting the right buccal mucosa.
Authors and Affiliations
Ruhi Sidhu, Navdeep Kooner Shergill, Parvathi Devi M, Santosh Kumar
Keywords
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