Wilms’ Tumour in an Adult- A Case Report of an Unusual Lesion
Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 8
Abstract
Wilms’ tumour, a renal malignancy, primarily occurs in children with a peak incidence between 2 to 5 years age group and accounts for approximately 95% of childhood renal malignancies. Though rarely, it may also occur in adults with an incidence rate of less than 0.2 per million per year. Microscopically, there is no difference between Wilms’ tumour of paediatric and adult age groups. But the prognosis for adults with Wilms’ tumour is thought to be worse than that for children possibly due to more aggressive clinical course in case of adult Wilms’ tumour. They are often associated with higher tumour stage at the time of presentation and outcome is often worse than paediatric age group possibly due to difficulty in diagnosis, inappropriate staging, and lack of standard treatment protocol. We report a case of 28-year-old lady presented with flank pain and abdominal lump. Abdominal CT scan showed a right renal mass suggestive of malignancy. A provisional diagnosis of renal cell carcinoma was made based on clinical and radiological findings. Nephrectomy was performed and a final morphological diagnosis of Wilms’ tumour was given. Immunohistochemical study showed strong Wilms’ Tumour 1(WT1) positivity in both blastemal and epithelial components confirming the morphological diagnosis. In view of its diagnostic difficulty and rare occurrence in adults, this case is being reported.
Authors and Affiliations
Goutam Bera, Zeenat Ara, Moumita Sengupta, Uttara Chatterjee, Madhumita Mukhopadhyay
Keywords
Related Articles
- EP ID EP358269
- DOI 10.7860/JCDR/2017/22957.10383
- Views 40
- Downloads 0
“Head Over Heels” Position of Duodenum-A Unique Congenital Anomaly
ABSTRACT Knowledge of congenital anomalies of duodenum and biliary apparatus is useful in radiological diagnosis and surgical procedures of upper abdominal region. We present concurrent variations of duodenum, bile duct...
Evaluation of the Potency of Kinetin on Radiation Induced Behavioural Changes in Swiss Albino Mice
Introduction: According to the various independent studies conducted, it is well evident fact that radiation induces oxidative stress in the living system. It is also proved that this oxidative stress will lead to the va...
The Effect of Entonox on Labour Pain Relief among Nulliparous Women: A Randomized Controlled Trial
Introduction: Labour pain is one of the most severe pain in humans. Fear of labour pain is the most dreadful reason for Caesarean Section (CS). Entonox (a mixture of nitrous oxide+oxygen) is a safe inhalational analgesia...
Remimazolam (CNS 7056): an Emerging Sedative and General Anaesthetic
ABSTRACT Remimazolam is a newer drug in the field of anaesthesia. It combines the properties of midazolam and remifentanil. As the name indicates, midazolam is the parent compound of remimazolam which incorporates the ph...
Predictive Performance of Quick Sequential Organ Failure Assessment Scoring in an Argentinian Hospital
ABSTRACT Introduction: The early identification and treatment of sepsis in emergency setting could improve patients’ survival. The Quick-SOFA score is a simple tool that could contribute to this identification. Aim: To...